1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-17
  5. IL-17A
  6. IL-17A 蛋白, Pig (N-His, C-Myc)

IL-17A 蛋白, Pig (N-His, C-Myc)

目录号: HY-P700632
产品使用指南

总之,IL-17A 参与多种免疫反应,并在维持上皮屏障完整性、促进中性粒细胞募集以及增强宿主对细菌、真菌和病毒感染的防御能力方面发挥着关键作用。IL-17A 蛋白, Pig (N-His, C-Myc) 是重组的 IL-17A 蛋白,由 E. coli 表达,带有 C-Myc, N-10*His 标签。IL-17A 蛋白, Pig (N-His, C-Myc) 全长 130 个氨基酸,分子量为 22.4 kDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

In summary, IL-17A participates in multiple immune responses and plays a critical role in maintaining epithelial barrier integrity, promoting neutrophil recruitment, and enhancing host defense against bacterial, fungal, and viral infections. IL-17A Protein, Pig (N-His, C-Myc) is the recombinant pig-derived IL-17A protein, expressed by E. coli , with C-Myc, N-10*His labeled tag. The total length of IL-17A Protein, Pig (N-His, C-Myc) is 130 a.a., with molecular weight of 22.4 kDa.

研究背景

IL-17A 蛋白是一种促炎细胞因子,在免疫反应和各种炎症性疾病的发病机制中发挥着关键作用。它参与免疫细胞的招募和促炎分子的产生。IL-17A 蛋白已成为治疗炎症性疾病的潜在治疗靶点,为开发新疗法提供了机会。

种属

Pig

表达系统

E. coli

标签

C-Myc;N-10*His

蛋白编号

Q60I29 (G24-S153)

基因 ID
蛋白结构
N-term
10*His
IL-17A (G24-S153)
Accession # Q60I29
Myc
C-term
同用名
Interleukin-17A; IL-17; IL-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; IL17A; CTLA8; IL17
氨基酸序列

GIMIPQSPGCPKTEDKNFPQHVRVNLNILNRSTPARRPSDYSKRFTSPWTLQRNEDPERYSSVIWEAKCSHSGCINAEGKEDHHMNSVPIQQEILVLRREPRHCPNSFRLEKVMVTVGCTCVTPIVRHIS

分子量

22.4 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

IL-17A Protein, Pig (N-His, C-Myc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IL-17A Protein, Pig (N-His, C-Myc)
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HY-P700632
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