IL-1R9/IL1RAPL2 蛋白, Human (HEK293, Fc)

Interleukin-1 (IL-1) is a receptor that mediates gene expression for the synthesis of proteins associated with inflammation.IL1RAPL2 is associated with non-syndromic X-linked mental retardation.IL1RAPL2 is specifically expressed in the nervous system and is a candidate gene for central nervous system diseases.IL-1R9/IL1RAPL2 Protein, Human (HEK293, Fc) is the recombinant human-derived IL-1R9/IL1RAPL2 protein, expressed by HEK293 , with C-hFc labeled tag.

白细胞介素-1 (Interleukin-1, IL-1) 通过受体介导炎症相关蛋白合成的基因表达。IL1RAPL2 蛋白是白细胞介素 1 受体家族的成员，与白细胞介素 1 受体辅助蛋白样 1 (IL1RAPL1) 相似。IL-1 在多发性肌炎和皮肌炎发病机制中起关键作用。IL1RAPL2 与非综合征性 X 连锁智力低下有关。IL1RAPL2 在神经系统中特异性表达，是中枢神经系统疾病的候选基因。

Measured by its ability to bind Human IL-1 alpha in functional ELISA.

Human

HEK293

C-hFc

Q9NP60 (T17-K354)

26280  [NCBI]

TNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYK

75-95 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.