IL1RAPL2 - interleukin 1 receptor accessory protein like 2 Gene

中文名称：白细胞介素 1 受体辅助蛋白样 2

种属: Homo sapiens

同用名: IL1R9; IL-1R9; TIGIRR-1; IL1RAPL-2

基因 ID: 26280 | 基因类型: protein coding

关于 IL1RAPL2

Cytogenetic location: Xq22.3 Genomic coordinates (GRCh38): X:104,566,199-105,767,829 (from NCBI)

This gene has 3 transcripts (splice variants), 122 orthologues and 10 paralogues. Low expression observed in reference dataset.

功能概要

由该基因编码的蛋白质是白介素 1 受体家族的成员。这种蛋白质类似于白细胞介素 1 辅助蛋白，与白细胞介素 1 受体辅助蛋白样 1 (IL1RAPL1) 关系最密切。该基因和 IL1RAPL1 位于 X 染色体上与 X 连锁非综合征性认知障碍相关的区域。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 1 (IL1RAPL1). This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic cognitive disability. [provided by RefSeq, Jul 2008]

IL1RAPL2 基因产物(1)

mRNA	Protein	Name
NM_017416.2	NP_059112.1	X-linked interleukin-1 receptor accessory protein-like 2 precursor

基因本体论

生物过程
细胞组分

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in regulation of presynapse assembly	IDA IDA: 通过直接分析推断	21926414	GOA
involved in regulation of presynapse assembly	IMP IMP: 通过突变表型推断	21926414	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
is active in glutamatergic synapse	IDA IDA: 通过直接分析推断	21926414	GOA
is active in glutamatergic synapse	IMP IMP: 通过突变表型推断	21926414	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IL1RAPL2 蛋白结构

Ig_2

Ig_3

TIR

0
200
400
600
686 a.a.

蛋白主名

其他名称

X-linked interleukin-1 receptor accessory protein-like 2

IL-1 receptor accessory protein-like 2

重组 IL1RAPL2 蛋白

目录号	产品名	蛋白编号	纯度
HY-P73151	IL-1R9/IL1RAPL2 Protein, Human (HEK293, Fc)	Q9NP60 (T17-K354)	≥95%
HY-P73895	IL-1R9/IL1RAPL2 Protein, Human (HEK293, His)	Q9NP60 (T17-E356)	≥95%

关联疾病

疾病名称

别名

Cinca Syndrome

CINCA	Nomid
Cryopyrin-Associated Periodic Syndrome 3	Chronic Neurologic Cutaneous And Articular Syndrome
Multisystem Inflammatory Disease, Neonatal-Onset	Caps3
Chronic Infantile Neurological Cutaneous Articular Syndrome	Infantile-Onset Multisystem Inflammatory Disease
Iomid Syndrome	Neonatal-Onset Multisystem Inflammatory Disease
Nomid Syndrome	Prieur-Griscelli Syndrome
Neonatal Onset Multisystem Inflammatory Disease	Chronic Infantile Neurological, Cutaneous And Articular Syndrome
Iomid	Infantile Onset Multisystem Inflammatory Disease
Prieur Griscelli Syndrome	Chronic Infantile Neurological Cutaneous And Articular Syndrome
Chronic, Infantile, Neurological, Cutaneous, Articular Syndrome	Chronic Infantile Neurologic Cutaneous And Articular Syndrome
Chronic Infantile Neurological, Cutaneous, And Articular Syndrome	Cryopyrin-Associated Periodic Syndromes

Muckle-Wells Syndrome

MWS	Urticaria-Deafness-Amyloidosis Syndrome
Uda Syndrome	Neutrophilic Urticaria
Urticaria, Deafness And Amyloidosis	Cryopyrin-Associated Periodic Syndrome 2
Caps2	Muckle Wells Syndrome
Urticaria-Deafness-Amyloidosis	Cryopyrin-Associated Periodic Syndromes

Adult-Onset Still'S Disease

Adult-Onset Still Disease	Adult Onset Still'S Disease
Adult Still'S Disease	Still'S Disease Adult Onset
Aosd	Wissler-Fanconi Syndrome
Stills Disease Adult-Onset	Still'S Disease, Adult-Onset
Wissler'S Syndrome

Gout

Gouty Arthritis	Articular Gout
Gouty Arthropathy	Arthritis, Gouty
Arthritis Gouty	Idiopathic Gout
Idiopathic Gout, Unspecified Site	Gouty Bursitis
Uratic Arthritis	Gout Nos
Gouty	Gouty Diathesis

Schnitzler Syndrome

Chronic Urticaria With Gammopathy	Chronic Urticaria With Macroglobulinemia
Chronic Urticaria With Gammapathy

Clostridium Difficile Colitis

Pseudomembranous Colitis	Colitis Pseudomembranous
Enterocolitis, Pseudomembranous	Pseudomembranous Enterocolitis
Clostridium Difficile Infection

Psoriatic Arthritis

Psoriatic Arthritis, Susceptibility To	Psoriatic Arthropathy
Arthropathic Psoriasis	Arthritis, Psoriatic
Arthritis Psoriatica	PSORAS
Arthritic Psoriasis	Psoriasis Arthropathica
Arthritis Psoriatic	Arthritis, Psoriatic, Susceptibility To

Blau Syndrome

Arthrocutaneouveal Granulomatosis	Jabs Syndrome
BLAUS	Sarcoidosis, Early-Onset
Acug	Granulomatous Inflammatory Arthritis, Dermatitis, And Uveitis, Familial
Eos	Granulomatosis, Familial Juvenile Systemic
Granulomatosis, Familial, Blau Type	Familial Juvenile Systemic Granulomatosis
Early Onset Sarcoidosis	Synovitis Granulomatous With Uveitis And Cranial Neuropathies
Early-Onset Sarcoidosis	Familial Granulomatosis, Blau Type
Pediatric Granulomatous Arthritis	Familial Granulomatosis Blau Type
Familial Granulomatous Inflammatory Arthritis Dermatitis And Uveitis	Synovitis, Granulomatous, With Uveitis And Cranial Neuropathies

Dengue Shock Syndrome

Dss

Cysticercosis

Neurocysticercosis	Submacular Cysticercosis
Intestinal Taenia Solium Infection	Pork Tapeworm Infection
Tapeworm Infection: Intestinal Taenia Solum	Tapeworm Infection: Pork
Tenia Solium Infectious Disease	Taeniasis
Tenia Solium Infection	Cysticerciasis Infection Due To Larval Form Of Taenia Solium

Dysentery

Infectious Diarrhea

Protein-Energy Malnutrition

PEM	Protein Energy Malnutrition

Scleritis

Rheumatoid Arthritis

RA	Arthritis, Rheumatoid
Rheumatoid Arthritis, Susceptibility To	Arthritis Or Polyarthritis, Rheumatic
Atrophic Arthritis	Rheumatism Arthritis
Rheumatoid Polyarthritis

Proteasome-Associated Autoinflammatory Syndrome 1

Jmp Syndrome	Nakajo-Nishimura Syndrome
Nkjo	Autoinflammation, Lipodystrophy, And Dermatosis Syndrome
Proteasome-Associated Autoinflammatory Syndrome 1 And Digenic Forms	Nakajo Syndrome
PRAAS1	Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy And Elevated Temperature Syndrome
Candle	Joint Contractures, Muscular Atrophy, Microcytic Anemia, And Panniculitis-Induced Lipodystrophy
Aldd	Inflammation
Joint Contractures - Muscle Atrophy - Microcytic Anemia - Panniculitis-Induced Lipodystrophy	Nakajo Nishimura Syndrome
Amyotrophy Fat Tissue Anomaly	Japanese Autoinflammatory Syndrome With Lipodystrophy
Jasl	Joint Contractures Muscular Atrophy Microcytic Anemia And Panniculitis-Induced Lipodystrophy
Nns	Nodular Erythema With Digital Changes
Secondary Hypertrophic Osteoperiostosis With Pernio

Indolent Plasma Cell Myeloma

Indolent Myeloma

Indolent Multiple Myeloma

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Autoimmune Disease

Autoimmune Diseases	Autoimmune Hypersensitivity Disease
Hypersensitivity Reaction Type Ii Disease	Type Ii Hypersensitivity Reaction Disease

Glycerol Kinase Deficiency

Hyperglycerolemia	GKD
Gk Deficiency	Gk1 Deficiency
Deficiency Of Glycerol Kinase	Isolated Glycerol Kinase Deficiency
Glycerol Kinase Deficiency, Adult Form	Glycerol Kinase Deficiency, Juvenile Form
Deficiency, Glycerol Kinase

Juvenile Rheumatoid Arthritis

Juvenile Idiopathic Arthritis	Juvenile Chronic Polyarthritis
Monarticular Juvenile Rheumatoid Arthritis	Pauciarticular Juvenile Arthritis
Still'S Disease	Systemic Juvenile Rheumatoid Arthritis
Juvenile Chronic Arthritis	Acute Juvenile Rheumatoid Arthritis
Pauciarticular Onset Juvenile Chronic Arthritis	Arthritis, Juvenile Rheumatoid
Jia	Jra
Juvenile Ra	Arthritis Juvenile Rheumatoid
Stills Disease	Juvenile Arthritis
Acute Polyarticular Juvenile Rheumatoid Arthritis	Pauciarticular Juvenile Rheumatoid Arthritis
Rheumatoid Arthritis, Systemic Juvenile

Psoriasis

Spondylarthropathy

Spondylarthropathies

Temporomandibular Joint Anomaly

Temporomandibular Joint Dysfunction	Temporomandibular Joint Disorder
Temporomandibular Joint Disease	Temporomandibular Jaw Disorder
Tmj - [Temporomandibular Joint] Disorder	Temporomandibular Developmental Disorder Of Jaw
Temporomandibular Dysfunction	Temporomandibular Joint Syndrome
Temporomandibular Joint-Pain-Dysfunction Syndrome	Mandibular Dysfunction Nos
Tmj - [Temporomandibular Joint Disorder] Syndrome	Tmjpds - [Temporomandibular Joint Pain Dysfunction Syndrome]
Tmj - [Temporomandibular Joint] Dysfunction

Osteoporosis

Postmenopausal Osteoporosis	Osteoporosis, Postmenopausal
Bone Mineral Density Quantitative Trait Locus	Bmnd
Osteoporosis, Involutional	Osteoporosis, Susceptibility To
Osteoporosis, Postmenopausal, Susceptibility	Bone Mineral Density Variation Qtl, Osteoporosis
OSTEOP	Involutional Osteoporosis
Senile Osteoporosis	Osteoporosis Postmenopausal
Bone Mineral Density, Quantitative Trait Locus	Osteoporosis, Senile
Idiopathic Osteoporosis	Bone Rarefaction Nos
Type 1 Osteoporosis

Systemic Lupus Erythematosus

Lupus Nephritis	SLE
Disseminated Lupus Erythematosus	Systemic Lupus Erythematosus, Susceptibility To
Lupus Erythematosus, Systemic	Lupus Nephritis, Susceptibility To
Libman-Sacks Disease	Systemic Lupus Erythematosus Susceptibility To
Sle - Lupus Erythematosus, Systemic	Le Syndrome
Lupus	Lupus Erythematosus Systemic
Lupus Erythematosus, Systemic, Susceptibility To	Lupus Vulgaris
Lupus Erythematosus, Discoid	Lupus Erythematosus
Systemic Lupus Erythematosus Nos	Sle - [Systemic Lupus Erythematosus]

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06724	IL1RAPL2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	IL1RAPL2	MGD	MGI:1913106
Macaca mulatta	IL1RAPL2	VGNC	VGNC:73720
Rattus norvegicus	IL1RAPL2	RGD	RGD:1561761
Others	IL1RAPL2	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

IL1RAPL2 - interleukin 1 receptor accessory protein like 2 Gene

关于 IL1RAPL2

功能概要

IL1RAPL2 基因产物(1)

IL1RAPL2 蛋白结构

重组 IL1RAPL2 蛋白

关联疾病

直系同源

热门区域

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IL1RAPL2 - interleukin 1 receptor accessory protein like 2 Gene

关于 IL1RAPL2

功能概要

IL1RAPL2 基因产物(1)

IL1RAPL2 蛋白结构

重组 IL1RAPL2 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z