IL-1R9/IL1RAPL2 蛋白, Human (HEK293, His)

Interleukin-1 (IL-1) is a receptor that mediates gene expression for the synthesis of proteins associated with inflammation. IL1RAPL2 is associated with non-syndromic X-linked mental retardation. IL1RAPL2 is specifically expressed in the nervous system and is a candidate gene for central nervous system diseases. IL-1R9/IL1RAPL2 Protein, Human (HEK293, His) is the recombinant human-derived IL-1R9/IL1RAPL2 protein, expressed by HEK293, with C-His labeled tag. The total length of IL-1R9/IL1RAPL2 Protein, Human (HEK293, His) is 340 a.a., with molecular weight of ~48-55 kDa.

白细胞介素-1 (IL-1) 是一种介导基因表达以合成与炎症相关的蛋白质的受体。IL1RAPL2 蛋白是白细胞介素 1 受体家族的成员，与白细胞介素 1 受体辅助蛋白样 1 (IL1RAPL1) 相似。IL-1在多发性肌炎和皮肌炎的发病机制中起着关键作用。IL1RAPL2 与非综合征型 X 连锁智力低下有关。IL1RAPL2 在神经系统中特异表达，是中枢神经系统疾病的候选基因^[1][2][3][4]。

Immobilized Human IL-1R9 at 0.5 μg/mL (100 μL/well) can bind Human PTPRD. The ED₅₀ for this effect is 136.4 ng/mL.

Human

HEK293

C-His

Q9NP60 (T17-E356)

26280  [NCBI]

Approximately 48-55 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.