1. 重组蛋白
  2. Cytokines and Growth Factors CD Antigens
  3. CSF & Receptors Stem Cell CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins
  4. IL-3R alpha/CD123
  5. IL-3R alpha/CD123 蛋白, Cynomolgus (HEK293, His)

IL-3R alpha/CD123 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P70461
COA 产品使用指南

IL-3R α/CD123蛋白是I型细胞因子受体家族的重要成员,介导细胞对多种细胞因子的反应,强调其在造血和免疫调节中的关键作用。IL-3R alpha/CD123 蛋白, Cynomolgus (HEK293, His) 是重组的 IL-3R α/CD123 蛋白,由 HEK293 表达,带有 C-6*His 标签。IL-3R alpha/CD123 蛋白, Cynomolgus (HEK293, His) 全长 285 个氨基酸,分子量为 50-65 kDa。

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
10 μg ¥720 In-stock
50 μg ¥2000 In-stock
100 μg   询价  

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描述

IL-3R α/CD123 protein is an important member of the type I cytokine receptor family and mediates cellular responses to a variety of cytokines, emphasizing its key role in hematopoiesis and immune regulation. IL-3R alpha/CD123 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-3R alpha/CD123 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IL-3R alpha/CD123 Protein, Cynomolgus (HEK293, His) is 285 a.a., with molecular weight of 50-65 kDa.

研究背景

IL-3R α/CD123 蛋白是 I 型细胞因子受体家族的重要成员,特别归类于 5 型亚家族,强调其在介导细胞对各种细胞因子的反应中的关键作用。作为该受体家族的一部分,IL-3R α/CD123 可能与相关受体具有保守的结构和功能特征,强调了其参与特定 I 型细胞因子信号的转导。I 型细胞因子受体家族的分类强调了其在更广泛的细胞信号传导背景下的特定名称,从而深入了解其对造血和免疫调节的独特贡献。IL-3R α/CD123 的研究有助于我们了解其在生理过程中的作用,并为造血障碍和免疫失调相关疾病的治疗干预提供了潜在的应用。对 IL-3R α/CD123 作用的进一步探索有望增强我们对其对正常细胞功能和病理状况的贡献的了解。

种属

Cynomolgus

表达系统

HEK293

标签

C-6*His

蛋白编号

G8F3K3 (R18-R302)

基因 ID

102138639

蛋白结构
N-term
IL-3Rα (R18-R302)
Accession # G8F3K3
6*His
C-term
同用名
Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; CD123
氨基酸序列

RTKEDPNAPIRNLRMKEKAQQLMWDLNRNVTDVECIKGTDYSMPAMNNSYCQFGAISLCEVTNYTVRVASPPFSTWILFPENSGTPRAGAENLTCWVHDVDFLSCSWVVGPAAPADVQYDLYLNNPNSHEQYRCLHYKTDARGTQIGCRFDDIAPLSRGSQSSHILVRGRSAAVSIPCTDKFVFFSQIERLTPPNMTGECNETHSFMHWKMKSHFNRKFRYELRIQKRMQPVRTEQVRDTTSFQLPNPGTYTVQIRARETVYEFLSAWSTPQRFECDQEEGASSR

分子量

50-65 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US;may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IL-3R alpha/CD123 Protein, Cynomolgus (HEK293, His)
目录号:
HY-P70461
需求量: