Integrin alpha 10 beta 1 蛋白, Human (HEK293, His)

Integrin alpha-10/beta-1, a collagen-specific receptor, crucially mediates cell interactions with the extracellular matrix. Comprising alpha-10 and beta-1 subunits, their stable association forms a heterodimeric complex. This interaction facilitates adhesion and signaling events, influencing essential aspects of cell behavior and tissue organization. Understanding Integrin alpha-10/beta-1's nuances provides insights into its significance in mediating cell-matrix interactions, offering implications in physiological and pathological contexts. Integrin alpha 10 beta 1 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 10 beta 1 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha 10 beta 1 Protein, Human (HEK293, His), has molecular weight of 140-160 kDa (ITGA10) & 100-130 kDa (ITGB), respectively.

整合素 α-10/β-1 是一种细胞表面受体，作为胶原蛋白的特异性受体发挥着关键作用，介导细胞与细胞外基质的相互作用。该整合素以异二聚体的形式发挥作用，由 α-10 亚基和 β-1 亚基组成。α-10 亚基与 β-1 亚基形成重要的关联，形成稳定的异二聚体复合物。通过这种相互作用，整合素 α-10/β-1 通过促进对胶原蛋白的粘附和信号传导事件来促进各种细胞过程，从而影响细胞行为和组织组织的关键方面。揭示整合素 α-10/β-1 相互作用的细微差别，有助于深入了解其在介导细胞-基质相互作用中的重要性及其在生理和病理背景下的潜在影响。

Human

HEK293

C-His

O75578-1 (F23-S1122)&P05556-1 (Q21-D728)

/

140-160 kDa (ITGA10) & 100-130 kDa (ITGB

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.