1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. JOSD1 蛋白, Human (GST)

JOSD1 蛋白, Human (GST)

目录号: HY-P701475
产品使用指南

JOSD1 蛋白是泛素动力学中的多功能参与者,并通过在体外裂解单泛素化探针来表现出去泛素酶活性。当泛素化时,JOSD1 可以在体外裂解“Lys-63”连接和“Lys-48”连接的多聚泛素链,表明其去泛素化的潜力。JOSD1 蛋白, Human (GST) 是重组的 JOSD1 蛋白,由 E. coli 表达,带有 N-GST 标签。JOSD1 蛋白, Human (GST) 全长 201 个氨基酸。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The JOSD1 protein is a versatile player in ubiquitin dynamics and exhibits deubiquitinase activity by cleaving monoubiquitinated probes in vitro. When ubiquitinated, JOSD1 can cleave “Lys-63”-linked and “Lys-48”-linked polyubiquitin chains in vitro, suggesting its potential for deubiquitination. JOSD1 Protein, Human (GST) is the recombinant human-derived JOSD1 protein, expressed by E. coli , with N-GST labeled tag. The total length of JOSD1 Protein, Human (GST) is 201 a.a., .

研究背景

JOSD1 蛋白是泛素动力学中的多功能参与者,通过在体外切割单泛素化探针来表现出去泛素酶活性。此外,当自身泛素化时,JOSD1 可以在体外裂解“Lys-63”连接和“Lys-48”连接的多聚泛素链,这表明其具有作为去泛素化酶的潜在作用。除了其催化功能外,JOSD1 还参与细胞过程,积极影响巨胞饮作用,同时抑制网格蛋白和小凹介导的内吞作用。值得注意的是,JOSD1 似乎独立于其酶活性而对膜动力学和细胞运动做出贡献,突出了其在协调细胞反应和稳态中的多方面作用。

种属

Human

表达系统

E. coli

标签

N-GST

蛋白编号

Q15040 (S2-V202)

基因 ID

9929

蛋白结构
N-term
GST
JOSD1 (S2-V202)
Accession # Q15040
C-term
同用名
JOSD1; Josephin-1; Josephin domain-containing protein 1
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

JOSD1 Protein, Human (GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
JOSD1 Protein, Human (GST)
目录号:
HY-P701475
需求量: