K-Cadherin/CDH6 蛋白, Cynomolgus (HEK293, His)

K-Cadherin/CDH6, a calcium-dependent cell adhesion protein, shows significant transcriptional expression in hepatocellular and renal carcinoma cell lines, hinting at potential involvement in metastasis and invasion. K-Cadherin/CDH6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived K-Cadherin/CDH6 protein, expressed by HEK293 , with C-His labeled tag.

K-钙粘蛋白，也称为 CDH6，代表钙依赖性细胞粘附蛋白的一个子集。K-钙粘蛋白在肝细胞和肾癌细胞系中表现出强转录表达，表明其可能在转移和侵袭中发挥作用。

Measured by the ability of the immobilized protein to support the adhesion of Caki‑2 human clear cell carcinoma epithelial cells. The ED₅₀ for this effect is 0.1204 μg/mL, corresponding to a specific activity is 8305.6478 units/mg.

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  Measured by the ability of the immobilized protein to support the adhesion of Caki‑2 human clear cell carcinoma epithelial cells. The ED₅₀ for this effect is 0.1204μg/mL， corresponding to a specific activity is 8305.6478 units/mg.

Cynomolgus

HEK293

C-His

G7MUQ7/XP_005556691 (T22-G614)

102144314  [NCBI]

TPLSKRTSGFPAKKRALELSGNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPHVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLRAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTG

85-95 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.