Kallikrein-5 蛋白, Mouse (HEK293, His)

The Kallikrein-5 protein may be involved in desquamation, suggesting a role in the process of skin shedding and exfoliation. Its association with desquamation suggests that it plays a role in regulating the removal of dead skin cells, which is critical for skin homeostasis. Kallikrein-5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kallikrein-5 protein, expressed by HEK293 , with C-His labeled tag. The total length of Kallikrein-5 Protein, Mouse (HEK293, His) is 264 a.a., with molecular weight of 40-50 kDa.

Kallikrein-5 蛋白似乎在脱屑中发挥潜在作用，表明其参与了皮肤脱落和剥落的复杂过程。它与脱屑的潜在联系意味着在调节死皮细胞去除方面的功能性作用，这是皮肤稳态的一个重要方面。值得注意的是，Kallikrein-5 活性被 Zn2+ 抑制，表明其酶功能的潜在调节机制。了解 Kallikrein-5 促进脱屑的具体机制以及 Zn2+ 的调节作用，可以为了解其在皮肤生理学中的功能提供有价值的见解，并阐明其在皮肤更新和维护相关过程中的潜在意义。对 Kallikrein-5 功能的进一步探索可能会加深我们对其在皮肤生物学中的作用及其在各种生理环境中的潜在影响的理解。

Measured by its ability to cleave the fluorogenic peptide 400 µM substrate BOC-Val-Pro-Arg-AMC (HY-137784) that incubate at room temperature in kinetic mode for 5 minutes.The specific activity is >1350 pmol/min/µg.

Mouse

HEK293

C-His

Q9D140 (G30-N293)

68668  [NCBI]

GDVSSCDNPSGTEPSGTNRDLSTDSKSGEDTRSDSSSRIVNGSDCQKDAQPWQGALLLGPNKLYCGAVLISPQWLLTAAHCRKPVFRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSHPGHSNDLMLIKMNRKIRDSHSVKPVEIACDCATEGTRCMVSGWGTTSSSHNNFPKVLQCLNITVLSEERCKNSYPGQIDKTMFCAGDEEGRDSCQGDSGGPVVCNGKLQGLVSWGDFPCAQRNRPGVYTNLCEFVKWIKDTMNSN

40-50 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末

Lyophilized from 0.22 μm filtered solution in 20 mM NaAc, 150 mM NaCl (pH 5.0). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in 20 mM NaAc, 150 mM NaCl (pH 5.0).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.