1. 重组蛋白
  2. Receptor Proteins
  3. Killer-Cell Immunoglobulin-like Receptors
  4. CD158b2/KIR2DL3
  5. KIR2DL3 蛋白, Human (HEK293, Fc)

KIR2DL3 蛋白, Human (HEK293, Fc)

目录号: HY-P75901
产品使用指南

KIR2DL3 存在于 NK 细胞上,选择性识别 HLA-C 等位基因,如 HLA-Cw1、HLA-Cw3 和 HLA-Cw7。它的相互作用会产生抑制作用,阻止 NK 细胞活性和细胞裂解。KIR2DL3 与 ARRB2 的关联强调了其在细胞信号通路中的作用,复杂地调节 NK 细胞功能。KIR2DL3 蛋白, Human (HEK293, Fc) 是重组的 KIR2DL3 蛋白,由 HEK293 表达,带有 C-hFc 标签。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

KIR2DL3, found on NK cells, selectively recognizes HLA-C alleles like HLA-Cw1, HLA-Cw3, and HLA-Cw7. Its interaction leads to inhibitory effects, preventing NK cell activity and cell lysis. KIR2DL3's association with ARRB2 underscores its role in cellular signaling pathways, intricately modulating NK cell functions. KIR2DL3 Protein, Human (HEK293, Fc) is the recombinant human-derived KIR2DL3 protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

KIR2DL3 在自然杀伤 (NK) 细胞上表达,作为特异性识别 HLA-C 等位基因(例如 HLA-Cw1、HLA-Cw3 和 HLA-Cw7)的受体发挥作用。通过这种相互作用,KIR2DL3 对 NK 细胞活性产生抑制作用,在防止细胞裂解方面发挥着至关重要的作用。该受体进一步与 ARRB2 结合,突显其参与调节 NK 细胞功能的复杂细胞信号传导途径。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

AAX23102.1 (H22-H245)

基因 ID
蛋白结构
N-term
KIR2DL3 (H22-H245)
Accession # AAX23102.1
hFc
C-term
同用名
Killer cell immunoglobulin-like receptor 2DL3; NKAT2a; NKAT-2; CD158b2; KIRCL23
分子量

Approximately 51.6 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

KIR2DL3 Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
KIR2DL3 Protein, Human (HEK293, Fc)
目录号:
HY-P75901
需求量: