LIFR 蛋白, Rat (HEK293, His)

LIFR protein is an important member of the type I cytokine receptor family, mediating cellular responses to a variety of cytokines, emphasizing its role in cell differentiation and immune regulation. LIFR Protein, Rat (HEK293, His) is the recombinant rat-derived LIFR protein, expressed by HEK293 , with C-His labeled tag.

LIFR 蛋白是 I 型细胞因子受体家族的重要成员，特别归类于 2 型亚家族，突出了其在介导细胞对各种细胞因子的反应中的重要作用。作为该受体家族的一部分，LIFR 可能与相关受体具有保守的结构和功能特征，强调其参与转导特定 I 型细胞因子的信号。I 型细胞因子受体家族的分类强调了其在更广泛的细胞信号传导背景下的特定名称，提供了对其对细胞分化和免疫调节等过程的独特贡献的见解。LIFR 的研究有助于我们了解其在生理过程中的作用，为细胞分化和免疫反应调节相关疾病的治疗干预提供了潜在的应用。对 LIFR 作用的进一步探索有望增强我们对其对正常细胞功能和病理状况的贡献的了解。

1.Measured by its binding ability in a functional ELISA. Immobilized Mouse LIF hFc at 2 μg/mL (100 μl/well) can bind Rat LIFR His , the EC₅₀ of Rat LIFR His is 300-700 ng/mL.
2.Measured by its ability to inhibit the recombinant human LIF mediated inhibition in the M1 mouse myeloid leukemia cells. The ED₅₀ for this effect is typically 5-40 ng/mL in the presence of 2 ng/mL recombinant human LIF.

Rat

HEK293

C-His

G3V7K2 (L44-S829)

81680  [NCBI]

Approximately 116 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.