2. Gene
  3. Lifr - LIF receptor subunit alpha Gene

Lifr - LIF receptor subunit alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81680 | 基因类型: protein coding

关于 Lifr

功能概要

Enables cytokine binding activity and Leukemia Inhibitory Factor receptor activity. Involved in several processes, including animal organ regeneration; negative regulation of muscle cell apoptotic process; and neuron projection morphogenesis. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in osteochondrodysplasia. Orthologous to human LIFR (LIF receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Lifr 基因产物(2)

mRNA Protein Name
NM_031048.1 NP_112310.1 leukemia inhibitory factor receptor precursor
NM_031048.1 NP_112310.1 leukemia inhibitory factor receptor precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine binding IMP
IMP: 通过突变表型推断
14638908 RGD
enables leukemia inhibitory factor receptor activity IMP
IMP: 通过突变表型推断
14638908 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IMP
IMP: 通过突变表型推断
14638908 RGD
involved in negative regulation of muscle cell apoptotic process IMP
IMP: 通过突变表型推断
15927854 RGD
involved in neuron projection morphogenesis IDA
IDA: 通过直接分析推断
12871977 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
16698589 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leukemia inhibitory factor receptor

LIF receptor alpha

LIF-R

leukemia inhibitor factor receptor alpha-chain

leukemia inhibitory factor receptor alpha

重组 Lifr 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75907 LIFR Protein, Rat (HEK293, His) G3V7K2 (L44-S829) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120142 EC359 Inducer 99.09% 否
HY-169192 BAR-2227 Agonist / 否
HY-RS07641 LIFR Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lifr NCBI NCBI:3977
Mus musculus Lifr NCBI NCBI:16880
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