LILRA6/CD85b/ILT8 蛋白, Human (HEK293, N-His)

LILRA6/CD85b/ILT-8 protein serves as a receptor for class I MHC antigens and plays a crucial role in immune recognition and regulation. Its interaction with class I MHC molecules has been shown to be involved in monitoring and potentially modulating immune responses. LILRA6/CD85b/ILT8 Protein, Human (HEK293, N-His) is the recombinant human-derived LILRA6/CD85b/ILT8 protein, expressed by HEK293 , with N-6*His labeled tag.

LILRA6/CD85b/ILT-8 蛋白似乎充当 I 类 MHC 抗原的受体，表明在免疫识别和调节中发挥着关键作用。它与 I 类 MHC 分子相互作用的能力表明它参与监测和潜在调节免疫反应。作为一种受体，LILRA6 可能有助于精确识别呈递 I 类 MHC 抗原的细胞，从而影响免疫活动。进一步探索 LILRA6 的相互作用及其对免疫信号的影响可以加深我们对其作为受体的作用及其在免疫监视和调节机制中的潜在影响的理解。

Measured in a cell proliferation assay using Jurkat human T-lymphocyte leukemia cells. The ED₅₀ for this effect is 0.2214 μg/ml, corresponding to a specific activity is 4.52×103 units/mg.

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  Measured in a cell proliferation assay using Jurkat human T-lymphocyte leukemia cells. The ED₅₀ for this effect is 0.2214 μg/mL, corresponding to a specific activity is 4.52×10³ units/mg.

Human

HEK293

N-6*His

Q6PI73-1 (G24-N447)

79168  [NCBI]

GPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPSTPASHAKDYTVEN

55-85 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.