2. 重组蛋白
  3. Others
  4. LRRC3B 蛋白, Human (HEK293, His)

LRRC3B 蛋白, Human (HEK293, His)

目录号: HY-P70894
产品使用指南

LRRC3B 蛋白是一种富含亮氨酸重复序列的跨膜蛋白。LRRC3B 是一种肿瘤抑制因子，参与癌发生，其表达在胃癌、乳腺癌、结肠癌、睾丸癌、前列腺癌和脑癌中下调。但LRRC3B在病毒感染组中表达上调。LRRC3B 参与植物和动物免疫、激素受体相互作用、细胞粘附、信号转导、基因表达调节和细胞凋亡 [3].LRRC3B 蛋白, Human (HEK293, His) 是重组的 LRRC3B 蛋白，由 HEK293 表达，带有 C-6*His 标签。LRRC3B 蛋白, Human (HEK293, His) 全长 171 个氨基酸，分子量约为 ~52.0 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

LRRC3B Protein is a leucine-rich repeat-containing transmembrane protein. LRRC3B, a tumor suppressor, is invovled in carcinogenesis, and the expression is down-regulated in gastric, breast, colon, testis, prostate, and brain cancers. But LRRC3B is up-regulated in the virus infected group. LRRC3B is involved in plant and animal immunity, hormone-receptor interactions, cell adhesion, signal transduction, regulation of gene expression, and apoptosis[1][2][3]. LRRC3B Protein, Human (HEK293, His) is the recombinant human-derived LRRC3B protein, expressed by HEK293, with C-6*His labeled tag. The total length of LRRC3B Protein, Human (HEK293, His) is 171 a.a., with molecular weight of ~52.0 kDa.
研究背景

富含亮氨酸重复序列的蛋白 3B (LRRC3B) 是一种富含亮氨酸重复序列的跨膜蛋白。LRRC3B 是一种肿瘤抑制因子，参与癌变过程，在胃癌、乳腺癌、结肠癌、睾丸癌、前列腺癌和脑癌中表达下调[1]。LRRC3B 参与植物和动物免疫、激素受体相互作用、细胞粘附、信号转导、基因表达调节和细胞凋亡[2]。此外，据报道，与对照组相比，病毒感染组的 LRRC3B 表达上调，表明 LRRC3B 参与免疫相关过程，通过激活 IFN 信号通路触发先天免疫反应[3]。
种属

Human
表达系统

HEK293
标签

C-6*His
蛋白编号

Q96PB8 (C34-Y204)
基因 ID
蛋白结构
N-term
LRRC3B (C34-Y204)
Accession # Q96PB8
6*His
C-term
同用名
Leucine-Rich Repeat-Containing Protein 3B; Leucine-Rich Repeat Protein LRP15; LRRC3B; LRP15
氨基酸序列

CPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDY

分子量

Approximately 52.0 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

LRRC3B Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
LRRC3B Protein, Human (HEK293, His)
目录号：
HY-P70894
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z