LSAMP 蛋白, Human (HEK293, His)

LSAMP proteins are key mediators that orchestrate selective neuronal growth and precise axonal targeting, playing a critical role in guiding axonal development and promoting mature circuit remodeling within the limbic system. Its importance extends to ensuring the normal growth of hippocampal mossy fiber projections, which contribute to the formation of complex neural pathway structures. LSAMP Protein, Human (HEK293, His) is the recombinant human-derived LSAMP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LSAMP Protein, Human (HEK293, His) is 287 a.a., with molecular weight of 45-65 kDa.

LSAMP 蛋白是协调选择性神经元生长和精确轴突靶向的关键介质，在引导轴突发育和促进边缘系统内成熟回路的重塑方面发挥着关键作用。该蛋白质的重要性延伸到其在确保海马苔藓纤维投射正常生长方面的重要作用，从而有助于形成复杂的神经通路结构。通过参与这些过程，LSAMP 成为神经发育错综复杂的协调过程中的关键参与者，影响发育过程中神经元连接的建立以及边缘系统成熟回路内的适应性变化。

Human

HEK293

C-6*His

Q13449 (V29-N315)

4045  [NCBI]

VRSVDFNRGTDNITVRQGDTAILRCVVEDKNSKVAWLNRSGIIFAGHDKWSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPTGREFEGEEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRPGSVRGIN

45-65 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.