LSAMP - limbic system associated membrane protein Gene

中文名称：边缘系统相关膜蛋白

种属: Homo sapiens

同用名: LAMP; IGLON3

关于 LSAMP

功能概要

该基因编码免疫球蛋白 LAMP、OBCAM 和 neurotrimin (IgLON) 蛋白家族的成员。编码的前原蛋白经过蛋白水解处理，生成神经元表面糖蛋白。 This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system.所编码的蛋白质也可能起到肿瘤抑制因子的作用，并可能在神经精神疾病中发挥作用。选择性剪接会产生多种转录物变体，其中至少一种会编码经过蛋白水解处理的前原蛋白。[RefSeq 提供，2016 年 1 月]

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]