Lymphocyte antigen 86/MD-1 蛋白, Mouse (HEK293, His)

Lymphocyte antigen 86/MD-1 acts synergistically with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and influence cytokine production.It plays a crucial role in promoting the high expression of CD180 on the cell surface, forming an M-shaped tetramer with two CD180-LY86 heterodimers.Lymphocyte antigen 86/MD-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Lymphocyte antigen 86/MD-1 protein, expressed by HEK293 , with C-His labeled tag.

淋巴细胞抗原 86/MD-1 蛋白作为 CD180 和 TLR4 的潜在合作者出现，介导对细菌脂多糖 (LPS) 的先天免疫反应并影响细胞因子的产生。此外，淋巴细胞抗原 86/MD-1 在促进 CD180 细胞表面高效表达方面发挥着至关重要的作用。结构排列涉及 M 形四聚体的形成，其中包含两个 CD180-LY86 异二聚体。这些特征强调了淋巴细胞抗原 86/MD-1 在协调免疫反应和细胞相互作用方面的多方面性质。进一步的探索对于揭示淋巴细胞抗原 86/MD-1 促进先天免疫系统复杂动态及其与 CD180 和 TLR4 协同响应细菌 LPS 的具体分子机制至关重要。

Mouse

HEK293

C-His

O88188 (M1-S162)

17084  [NCBI]

24-30 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.