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  3. MAGP-2/MFAP5 蛋白, Human (HEK293, hFc)

MAGP-2/MFAP5 蛋白, Human (HEK293, hFc)

目录号: HY-P702772
产品使用指南

MAGP-2/MFAP5蛋白可能影响造血并参与血细胞形成。在心血管系统中,它调节生长因子,通过细胞信号传导维持大血管的完整性,并有助于弹性蛋白相关微纤维的结构组织。MAGP-2/MFAP5 蛋白, Human (HEK293, hFc) 是重组的 MAGP-2/MFAP5 蛋白,由 HEK293 表达,带有 C-hFc 标签。

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描述

MAGP-2/MFAP5 protein may affect hematopoiesis and participate in blood cell formation. In the cardiovascular system, it regulates growth factors, maintains the integrity of large blood vessels through cell signaling, and contributes to the structural organization of elastin-associated microfibrils. MAGP-2/MFAP5 Protein, Human (HEK293, hFc)is the recombinant human-derived MAGP-2/MFAP5 protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

MAGP-2/MFAP5 蛋白被认为可能在造血过程中发挥作用,表明其参与与血细胞形成相关的关键过程。在心血管系统中,有人提出调节生长因子或参与细胞信号传导以维持大血管的完整性。值得注意的是,MAGP-2/MFAP5 作为弹性蛋白相关微纤维的组成部分,有助于这些细胞外基质元素的结构组织。此外,它还与 TGFB2 和 BMP2 等关键信号分子相互作用,表明其在调节信号通路中发挥作用。此外,MAGP-2/MFAP5 与 FBN1 和 FBN2 相互作用,强调其参与与原纤维相关的蛋白质动态网络,并有助于组织结构和功能的整体维持。MAGP-2/MFAP5 的多方面功能和分子相互作用强调了其在造血和心血管稳态中的重要性。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q13361-1 (I22-L173)

基因 ID

8076

同用名
Microfibrillar-associated protein 5; MFAP-5; MP25; MAGP-2
氨基酸序列

IPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDDLASLSEKNTTAECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL

分子量

Approximately 32-38 kDa and 55-65 kDa, Due to furin cleavage and glycosylation.

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

MAGP-2/MFAP5 Protein, Human (HEK293, hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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MAGP-2/MFAP5 Protein, Human (HEK293, hFc)
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HY-P702772
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