MAGP-2/MFAP5 蛋白, Human (His-SUMO)

MAGP-2/MFAP5 protein may affect hematopoiesis and participate in blood cell formation. In the cardiovascular system, it regulates growth factors, maintains the integrity of large blood vessels through cell signaling, and contributes to the structural organization of elastin-associated microfibrils. MAGP-2/MFAP5 Protein, Human (His-SUMO) is the recombinant human-derived MAGP-2/MFAP5 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

MAGP-2/MFAP5 蛋白被认为可能在造血过程中发挥作用，表明其参与与血细胞形成相关的关键过程。在心血管系统中，有人提出调节生长因子或参与细胞信号传导以维持大血管的完整性。值得注意的是，MAGP-2/MFAP5 作为弹性蛋白相关微纤维的组成部分，有助于这些细胞外基质元素的结构组织。此外，它还与 TGFB2 和 BMP2 等关键信号分子相互作用，表明其在调节信号通路中发挥作用。此外，MAGP-2/MFAP5 与 FBN1 和 FBN2 相互作用，强调其参与与原纤维相关的蛋白质动态网络，并有助于组织结构和功能的整体维持。MAGP-2/MFAP5 的多方面功能和分子相互作用强调了其在造血和心血管稳态中的重要性。

Human

E. coli

N-SUMO;N-6*His

Q13361-1 (I22-L173)

8076

IPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDDLASLSEKNTTAECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL

Approximately 36 kDa.

Greater than 90% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.