MBL2/COLEC1 蛋白, Mouse (HEK293)

C-type lectin domain-containing protein is a soluble mannose-binding protein in serum which belongs to the collectin family and is an important element in the innate immune system. C-type lectin domain-containing protein exerts mannose-binding, calcium-dependent protein binding and identical protein binding activity. MBL2/COLEC1 Protein, Mouse (HEK293) is the recombinant mouse-derived MBL2/COLEC1 protein, expressed by HEK293 , with tag free.

C 型凝集素结构域蛋白 (C-type lectin domain-containing protein) 是一种血清中的可溶性甘露糖结合蛋白，属于凝集素家族，是固有免疫系统的重要组成部分。包含 C 型凝集素结构域的蛋白可识别并结合许多微生物上的甘露糖和 N-乙酰氨基葡萄糖，包括细菌、酵母和病毒 (包括流感病毒、HIV 和 SARS-CoV)。这种结合激活经典补体途径。含有 C 型凝集素结构域的蛋白质也具有钙依赖性蛋白结合活性和相同的蛋白结合活性。C 型凝集素结构域蛋白缺陷可能与自身免疫性疾病、感染性疾病、肝脏和肺部疾病的易感性有关^[1][2]。

Mouse

HEK293

Tag Free

Q3UEK1 (E19-D244)

17195  [NCBI]

ETLTEGVQNSCPVVTCSSPGLNGFPGKDGRDGAKGEKGEPGQGLRGLQGPPGKVGPTGPPGNPGLKGAVGPKGDRGDRAEFDTSEIDSEIAALRSELRALRNWVLFSLSEKVGKKYFVSSVKKMSLDRVKALCSEFQGSVATPRNAEENSAIQKVAKDIAYLGITDVRVEGSFEDLTGNRVRYTNWNDGEPNNTGDGEDCVVILGNGKWNDVPCSDSFLAICEFSD

Approximately 28.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.