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  3. MLANA 蛋白, Human (His, B2M)

MLANA 蛋白, Human (His, B2M)

目录号: HY-P71544
产品使用指南

MLANA蛋白在黑素体生物合成中至关重要,确保GPR143的稳定性,并在黑素细胞蛋白PMEL的表达、稳定性、运输和加工中发挥关键作用。它与 PMEL 和 GPR143 的相互作用凸显了它在第二阶段黑素体形成所需的复杂网络中的不可或缺的作用。MLANA 蛋白, Human (His, B2M) 是重组的 MLANA 蛋白,由 E. coli 表达,带有 N-His, B2M 标签。

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描述

The MLANA protein is essential in melanosome biosynthesis, ensuring the stability of GPR143, and plays a key role in the expression, stability, transport, and processing of the melanocyte protein PMEL. Its interaction with PMEL and GPR143 highlights its integral role in the complex network required for second-stage melanosome formation. MLANA Protein, Human (His, B2M) is the recombinant human-derived MLANA protein, expressed by E. coli , with N-His, B2M labeled tag.

研究背景

MLANA 蛋白是黑素体生物合成中不可或缺的一部分,可确保 GPR143 的稳定性,并在黑素细胞蛋白 PMEL 的表达、稳定性、运输和加工中发挥至关重要的作用。它参与这些过程对于第二阶段黑素体的形成至关重要。MLANA 与 PMEL 和 GPR143 相互作用,确立其在黑素体发育所需的复杂蛋白质相互作用网络中的作用。这些相互作用的协调强调了 MLANA 在黑素细胞生物学和黑素体生物发生中的重要性。

种属

Human

表达系统

E. coli

标签

N-His;B2M

蛋白编号

Q16655 (M1-P118)

基因 ID
蛋白结构
N-term
6*His-B2M
MLANA (M1-P118)
Accession # Q16655
C-term
同用名
Antigen LB39 AA; Antigen LB39-AA; Antigen SK29 AA; Antigen SK29-AA; MAR1_HUMAN; MART 1; MART-1; MART1; Melan A; Melan A protein; Melanoma antigen recognized by T cells 1; Melanoma antigen recognized by T-cells 1; MLAN A; MLANA; OTTHUMP00000021036; OTTHUMP00000021037; OTTHUMP00000021038; Protein Melan-A
氨基酸序列

MPREDAHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVLLLIGCWYCRRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP

分子量

Approximately 27.2 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

MLANA Protein, Human (His, B2M) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
MLANA Protein, Human (His, B2M)
目录号:
HY-P71544
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