1. 重组蛋白
  2. Enzymes & Regulators
  3. Matrix Metalloproteinases
  4. MMP-9
  5. MMP-9 蛋白, Cynomolgus (HEK293, His)

MMP-9 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P700893
产品使用指南

MMP-9 蛋白是一种基质金属蛋白酶,对于局部细胞外基质蛋白水解和白细胞迁移至关重要。提示其可能参与骨破骨细胞吸收。MMP-9 蛋白, Cynomolgus (HEK293, His) 是重组的 MMP-9 蛋白,由 HEK293 表达,带有 C-His 标签。MMP-9 蛋白, Cynomolgus (HEK293, His) 全长 687 个氨基酸,分子量为 85-100 kDa。

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描述

The MMP-9 protein is a matrix metalloproteinase that is critical for local extracellular matrix proteolysis and leukocyte migration. It is suggested that it may be involved in bone osteoclastic resorption. MMP-9 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MMP-9 protein, expressed by HEK293 , with C-His labeled tag. The total length of MMP-9 Protein, Cynomolgus (HEK293, His) is 687 a.a., with molecular weight of 85-100 kDa.

研究背景

MMP-9 蛋白是一种基质金属蛋白酶,在细胞外基质的局部蛋白水解中发挥着至关重要的作用,并促进白细胞迁移。它可能参与骨破骨细胞吸收并在特定的 Gly-|-Leu 键处裂解 KiSS1。此外,MMP-9 裂解 NINJ1 以生成分泌型 ninjurin-1 形式,并将 IV 型和 V 型胶原加工成较大的 C 端四分之三片段和较短的 N 端四分之一片段。在降解纤连蛋白时,MMP-9 不会影响层粘连蛋白或 Pz 肽,显示出其在底物裂解中的选择性。

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

A0A2K5UU71 (A20-D706)

基因 ID

102117693

蛋白结构
N-term
MMP-9 (A20-D706)
Accession # A0A2K5UU71
His
C-term
同用名
MMP-9; GELB; CLG4B; MANDP2; Gelatinase B
分子量

85-100 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

MMP-9 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
MMP-9 Protein, Cynomolgus (HEK293, His)
目录号:
HY-P700893
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