2. 重组蛋白
  3. Immune Checkpoint Proteins CD Antigens Receptor Proteins
  4. Inhibitory Checkpoint Molecules NK Cell CD Proteins Platelet CD Proteins Erythrocyte CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  5. Nectin-1/CD111 Immunoglobulin-like Cell Adhesion Molecules
  6. Nectin-1 蛋白, Rat (HEK293, Fc)

Nectin-1 蛋白, Rat (HEK293, Fc)

目录号: HY-P77470
产品使用指南

Nectin-1 蛋白具有碳水化合物和病毒粒子结合活性，在轴突引导、突触组装和病毒进入中发挥着关键作用。Nectin-1 位于树突、生长锥膜和突触中，与唇裂和外胚层发育不良等人类疾病有关。它的偏向表达，特别是在肾脏 (RPKM 45.4) 和大脑 (RPKM 31.3) 中，强调了它在不同生理环境中的重要性。Nectin-1 蛋白, Rat (HEK293, Fc) 是重组的 Nectin-1 蛋白，由 HEK293 表达，带有 C-hFc 标签。

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描述

Nectin-1 Protein, with carbohydrate and virion binding activities, plays pivotal roles in axon guidance, synapse assembly, and viral entry. Located in dendrites, growth cone membranes, and synapses, Nectin-1 is implicated in human conditions like cleft lip and ectodermal dysplasia. Its biased expression, especially in Kidney (RPKM 45.4) and Brain (RPKM 31.3), underscores its significance in diverse physiological contexts. Nectin-1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Nectin-1 protein, expressed by HEK293 , with C-hFc labeled tag.
研究背景

Nectin-1 蛋白以其碳水化合物结合和病毒粒子结合活性为特征，在轴突引导、突触组装调节和病毒进入宿主细胞中发挥着关键作用。Nectin-1 分布在各种细胞成分中，包括树突、生长锥膜和突触，与唇裂、唇腭裂外胚层发育不良综合征、腭裂和外胚层发育不良等人类疾病有关。这种偏向的表达模式，特别是在肾脏 (RPKM 45.4)、脑 (RPKM 31.3) 和其他九个组织中，强调了其在不同生理环境中的重要性。
种属

Rat
表达系统

HEK293
标签

C-hFc
蛋白编号

F1LNP8/NP_001093946 (Q31-A354)
基因 ID
蛋白结构
N-term
Nectin-1 (Q31-A354)
Accession # F1LNP8/NP_001093946
hFc
C-term
同用名
Poliovirus Receptor-Related Protein 1; Herpes Virus Entry Mediator C; Herpesvirus Entry Mediator C; HveC; Herpesvirus Ig-Like Receptor; HIgR; Nectin-1; CD111; PVRL1; HVEC; PRR1
分子量

88-98 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Nectin-1 Protein, Rat (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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