2. 重组蛋白
  3. Others
  4. NEU2 蛋白, Cricetulus griseus (Baculovirus, His-Myc)

NEU2 蛋白, Cricetulus griseus (Baculovirus, His-Myc)

目录号: HY-P72062
产品使用指南

NEU2 蛋白通过催化从糖蛋白、寡糖和神经节苷脂中去除唾液酸（N-乙酰神经氨酸）部分，在细胞过程中发挥关键作用。通过其酶活性，NEU2 有助于细胞表面糖复合物的受控修饰，影响各种细胞功能，包括细胞粘附、信号传导和免疫反应。NEU2 蛋白, Cricetulus griseus (Baculovirus, His-Myc) 是重组的 NEU2 蛋白，由 Sf9 insect cells 表达，带有 N-10*His, C-Myc 标签。NEU2 蛋白, Cricetulus griseus (Baculovirus, His-Myc) 全长 379 个氨基酸，分子量约为 ~45.8 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The NEU2 protein plays a key role in cellular processes by catalyzing the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins, oligosaccharides, and gangliosides. Through its enzymatic activity, NEU2 contributes to the controlled modification of cell surface glycoconjugates, affecting various cellular functions including cell adhesion, signaling, and immune responses. NEU2 Protein, Cricetulus griseus (Baculovirus, His-Myc) is the recombinant NEU2 protein, expressed by Sf9 insect cells , with N-10*His, C-Myc labeled tag. The total length of NEU2 Protein, Cricetulus griseus (Baculovirus, His-Myc) is 379 a.a., with molecular weight of ~45.8 kDa.
研究背景

NEU2 蛋白是一种酶，通过催化糖蛋白、寡糖和神经节苷脂中唾液酸（N-乙酰神经氨酸）部分的去除，在唾液酸代谢中发挥至关重要的作用。这种酶活性有助于调节细胞表面糖缀合物和细胞相互作用。NEU2 介导的去唾液酸化可以影响糖蛋白的识别和功能，从而影响细胞粘附、信号传导和免疫反应等过程。NEU2 去除唾液酸对于调节整体聚糖结构和功能至关重要，对各种生理和病理条件具有潜在影响。参考资料：所提供的信息基于截至 2022 年 1 月的一般知识，未引用具体参考资料。
种属

Others
表达系统

Sf9 insect cells
标签

N-10*His;C-Myc
蛋白编号

Q64393 (M1-Q379)
基因 ID

100689301  [NCBI]
蛋白结构
N-term
10*His
NEU2 (M1-Q379)
Accession # Q64393
Myc
C-term
同用名
NEU2; Sialidase-2; EC 3.2.1.18; Cytosolic sialidase; N-acetyl-alpha-neuraminidase 2
氨基酸序列

MATCPVLQKETLFQTGDYAYRIPALIYLSKQKTLLAFAEKRLTKTDEHADLFVLRRGSYNADTHQVQWQAEEVVTQAYLEGHRSMSPCPLYDKQTRTLFLFFIAVRGQISEHHQLQTGVNVTRLCHITSTDHGKTWSAVQDLTDTTIGSTHQDWATFGVGPGHCLQLRNTAGSLLVPAYAYRKQPPIHAPAPSAFCFLSHDHGSTWELGHFVSQNSLECQVAEVGTGAERVVYLNARSCLGARVQAQSPNSGLDFQDNQVVSKLVEPPKGCHGSVIAFPNPTSKADALDVWLLYTHPTDSRKRTNLGVYLNQKPLDPTTWSAPTLLATGICAYSDLQNMGHGPDGSPQFGCLYESNNYEEIVFLMFTLKQAFPAVFGAQ

分子量

Approximately 45.8 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

NEU2 Protein, Cricetulus griseus (Baculovirus, His-Myc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
NEU2 Protein, Cricetulus griseus (Baculovirus, His-Myc)
目录号：
HY-P72062
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z