Neurotrophin-4 蛋白, Human (HEK293)

Neurotrophin-4 (NT-4) protein serves as a vital target-derived survival factor for peripheral sensory sympathetic neurons, emphasizing its crucial role in promoting their survival and maintenance. The specific and targeted actions of NT-4 underscore its significance as a neurotrophic factor in the intricate mechanisms governing the well-being of peripheral neurons within the sympathetic nervous system. Neurotrophin-4 Protein, Human (HEK293) is the recombinant human-derived Neurotrophin-4 protein, expressed by HEK293 , with tag free. The total length of Neurotrophin-4 Protein, Human (HEK293) is 130 a.a., with molecular weight of 14 kDa.

Neurotropin-4 (NT-4) 蛋白是一种重要的靶标衍生生存因子，专门针对外周感觉交感神经元。其关键作用在于支持这些神经元的生存和维持，强调 NT-4 在促进外周感觉交感神经元的健康和功能方面的重要性。NT-4 的特异性和靶向作用强调了其作为神经营养因子的作用，在控制交感神经系统内周围神经元生存和健康的复杂机制中发挥着关键作用。

Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with TrkB. The ED₅₀ for this effect is 2.337 ng/mL, corresponding to a specific activity is 4.279×10^5 units/mg.

Human

HEK293

Tag Free

P34130 (G81-A210)

4909

Approximately 14 kDa band in SDS-PAGE under reducing conditions.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of 0.1% TFA, 20% Acetonitrile, pH 2.5.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.