Neurturin 蛋白, Human

Neurturin protein, vital in neurobiology, is key to supporting sympathetic neuron survival and implicated in regulating the central nervous system (CNS). It influences neural growth, stability, and may modulate non-neuronal cell populations. Neurturin, a homodimer linked by disulfide bonds, maintains structural integrity for diverse cellular functions beyond neuronal survival. Neurturin Protein, Human is the recombinant human-derived Neurturin protein, expressed by E. coli , with tag free. The total length of Neurturin Protein, Human is 102 a.a., with molecular weight of ~15.0 kDa.

Neurturin 蛋白是神经生物学中的重要因素，在支持培养物中交感神经元的存活方面发挥着关键作用。除了在神经元存活中的作用外，Neurturin 还被认为在中枢神经系统 (CNS) 的发育和维护中具有调节功能，影响控制神经生长和稳定性的复杂过程。此外，它还可能参与调节非神经元细胞群（例如造血细胞）的大小，强调了其对细胞动力学的更广泛影响。Neurturin 作为同二聚体发挥作用，通过二硫键连接在一起，强调其在执行多种细胞功能时的结构完整性。

Human

E. coli

Tag Free

Q99748 (A96-V197)

4902  [NCBI]

ARLGARPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECACV

Approximately 15.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20mM Citrate, 6% Sucrose, 4% Mannitol, 0.05% Tween 80, pH 4.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.