1. 重组蛋白
  2. CAR-T related Proteins CD Antigens
  3. CD314/NKG2D T Cell CD Proteins NK Cell CD Proteins
  4. CD314/NKG2D
  5. NKG2D/CD314 蛋白, Mouse (sf9, Fc)

NKG2D/CD314 蛋白, Mouse (sf9, Fc)

目录号: HY-P76513
产品使用指南

NKG2D 是一种活化性细胞表面受体,它与携带 yxxm 的衔接蛋白 DAP10 选择性结合。NKG2D/CD314 蛋白, Mouse (sf9, Fc) 是重组的 NKG2D/CD314 蛋白,由 Sf9 insect cells 表达,带有 N-hFc 标签。

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描述

NKG2D is an activating cell surface receptor that associates selectively with DAP10, an YxxM-bearing adaptor protein.NKG2D/CD314 Protein, Mouse (sf9, Fc) is the recombinant mouse-derived NKG2D/CD314 protein, expressed by Sf9 insect cells , with N-hFc labeled tag.

研究背景

NKG2D 是一种活化的细胞表面受体,据报道它与携带 yxxm 的衔接蛋白 DAP10 选择性结合。NKG2D 具有多种功能,包括 MHC I 类蛋白结合活性、MHC I 类 b 受体活性和相同的蛋白结合活性。NKG2D 参与自然杀伤细胞介导的细胞毒性的正向调节。NKG2D 作用于多个过程的上游或内部,包括正向调节 γ 干扰素的产生,正向调节一氧化氮的生物合成过程和对细菌的反应。NKG2D 位于细胞质膜的外侧面[1][2][3]

种属

Mouse

表达系统

Sf9 insect cells

标签

N-hFc

蛋白编号

Q4FJM0 (F77-V219)

基因 ID
蛋白结构
N-term
hFc
NKG2D (F77-V219)
Accession # Q4FJM0
C-term
同用名
NKG2-D type II integral membrane protein; NK cell receptor D; CD314; KLRK1; D12S2489E
分子量

Approximately 44.9 kDa.

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
NKG2D/CD314 Protein, Mouse (sf9, Fc)
目录号:
HY-P76513
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