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  2. Klrk1 - killer cell lectin-like receptor subfamily K, member 1 Gene

Klrk1 - killer cell lectin-like receptor subfamily K, member 1 Gene

种属: Mus musculus

同用名: Nkg2d; NKG2-D; D6H12S2489E

基因 ID: 27007 | 基因类型: protein coding

关于 Klrk1

功能概要

Enables several functions, including MHC class I protein binding activity; MHC class Ib receptor activity; and identical protein binding activity. Involved in positive regulation of natural killer cell mediated cytotoxicity. Acts upstream of or within several processes, including positive regulation of interferon-gamma production; positive regulation of nitric oxide biosynthetic process; and response to bacterium. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in tropical spastic paraparesis. Orthologous to several human genes including KLRC4-KLRK1 (KLRC4-KLRK1 readthrough). [provided by Alliance of Genome Resources, Apr 2022]

Klrk1 基因产物(3)

mRNA Protein Name
NM_001083322.2 NP_001076791.1 NKG2-D type II integral membrane protein isoform b
NM_001286018.1 NP_001272947.1 NKG2-D type II integral membrane protein isoform c
NM_033078.4 NP_149069.1 NKG2-D type II integral membrane protein isoform a
蛋白主名 其他名称

NKG2-D type II integral membrane protein

NK cell receptor D

NKG2-D-activating NK receptor

natural killer cell group 2D

重组 Klrk1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72503 NKG2D/CD314 Protein, Mouse (HEK293, His) O54709 (F94-V232) ≥95%
HY-P76513 NKG2D/CD314 Protein, Mouse (sf9, Fc) Q4FJM0 (F77-V219) ≥95%
HY-P78330 NKG2D/CD314 Protein, Mouse (HEK293, Fc) O54709 (F90-V232) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Klrk1 NCBI NCBI:22914
Macaca fascicularis Klrk1 NCBI
Macaca mulatta Klrk1 NCBI