NPTXR 蛋白, Human (HEK293, His)

The NPTXR protein may mediate synaptic processes, suggesting its involvement in synaptic material uptake during remodeling or AMPA receptor clustering at specific excitatory synapses. These effects suggest that NPTXR dynamically regulates synaptic structure and function. NPTXR Protein, Human (HEK293, His) is the recombinant human-derived NPTXR protein, expressed by HEK293 , with N-His labeled tag. The total length of NPTXR Protein, Human (HEK293, His) is 477 a.a., with molecular weight of 55-75 KDa.

NPTXR 蛋白作为突触过程中的潜在介质出现，表明其参与突触重塑过程中突触物质的摄取或特定兴奋性突触处 AMPA 谷氨酸受体的突触聚集。这些作用表明 NPTXR 参与突触结构和功能的动态调节。阐明 NPTXR 参与突触重塑和 AMPA 受体聚类的精确机制，可以为了解其对突触可塑性和神经传递的贡献提供有价值的见解。对 NPTXR 功能的进一步探索可能会加深我们对其在各种神经元过程中的具体含义及其在维持突触完整性和功能方面的潜在意义的理解。

Measured by the ability of the immobilized protein to support the adhesion of U87 human glioblastoma/astrocytoma cells. The ED₅₀ for this effect is 0.1499 μg/mL, corresponding to a specific activity is 6.67×10³units/mg.

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  Measured by the ability of the immobilized protein to support the adhesion of U87 human glioblastoma/astrocytoma cells. The ED₅₀ for this effect is 0.1499 μg/mL, corresponding to a specific activity is 6.67×10³ units/mg.

Human

HEK293

N-10*His

O95502 (A24-A500)

23467  [NCBI]

ASVPLAASPARALPGGADNASVASGAAASPGPQRSLSALHGAGGSAGPPALPGAPAASAHPLPPGPLFSRFLCTPLAAACPSGAQQGDAAGAAPGEREELLLLQSTAEQLRQTALQQEARIRADQDTIRELTGKLGRCESGLPRGLQGAGPRRDTMADGPWDSPALILELEDAVRALRDRIDRLEQELPARVNLSAAPAPVSAVPTGLHSKMDQLEGQLLAQVLALEKERVALSHSSRRQRQEVEKELDVLQGRVAELEHGSSAYSPPDAFKISIPIRNNYMYARVRKALPELYAFTACMWLRSRSSGTGQGTPFSYSVPGQANEIVLLEAGHEPMELLINDKVAQLPLSLKDNGWHHICIAWTTRDGLWSAYQDGELQGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTAPLLGNVLPWEDKLVEAFGGATKAAFDVCKGRAKA

Approximately 55-75 kDa due to the glycosylation

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.