1. 重组蛋白
  2. Receptor Proteins
  3. NPY2R 蛋白, Human (Cell-Free, His)

NPY2R 蛋白, Human (Cell-Free, His)

目录号: HY-P702389
产品使用指南

NPY2R、神经肽 Y (NPY) 和肽 YY (PYY) 受体对胰肽表现出不同的亲和力。按降序排列的偏好包括 PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [ Pro - 34] PYY 和 NPY 游离酸。NPY2R 蛋白, Human (Cell-Free, His) 是重组的 NPY2R 蛋白,由 E. coli Cell-free 表达,带有 N-10*His 标签。NPY2R 蛋白, Human (Cell-Free, His) 全长 381 个氨基酸,分子量为 48.8 kDa。

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描述

NPY2R, the neuropeptide Y (NPY) and peptide YY (PYY) receptors, exhibit different affinities for pancreatic peptides. Preferences in descending order include PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [ Pro -34] PYY and NPY free acids. NPY2R Protein, Human (Cell-Free, His) is the recombinant human-derived NPY2R protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of NPY2R Protein, Human (Cell-Free, His) is 381 a.a., with molecular weight of 48.8 kDa.

研究背景

NPY2R 是神经肽 Y (NPY) 和肽 YY (PYY) 的受体,对各种胰腺多肽表现出不同的亲和力。该受体的结合偏好按亲和力降序排列如下:PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31、Pro-34] NPY > PP、[Pro-34] PYY 和 NPY 游离酸。该受体对不同形式的胰腺多肽的细微反应强调了其在选择性识别这些信号分子并与其相互作用中的作用,从而促进了神经肽 Y 和肽 YY 介导的多种生理效应。

种属

Human

表达系统

E. coli Cell-free

标签

N-10*His

蛋白编号

P49146 (M1-V381)

基因 ID

4887

蛋白结构
N-term
10*His
NPY2R (M1-V381)
Accession # P49146
C-term
同用名
Neuropeptide Y receptor type 2; NPY-Y2 receptor; Y2 receptor
氨基酸序列

MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV

分子量

48.8 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

NPY2R Protein, Human (Cell-Free, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
NPY2R Protein, Human (Cell-Free, His)
目录号:
HY-P702389
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