2. 重组蛋白
  3. Receptor Proteins
  4. Pattern Recognition Receptors
  5. C-type Lectin Receptors
  6. CLEC2D
  7. OCIL/CLEC2D 蛋白, Human (Biotinylated, HEK293, Fc-Avi)

OCIL/CLEC2D 蛋白, Human (Biotinylated, HEK293, Fc-Avi)

目录号: HY-P77902
产品使用指南

OCIL/CLEC2D 蛋白充当 KLRB1 的受体，保护靶细胞免受自然杀伤细胞介导的裂解。它不仅能抑制破骨细胞的形成和骨吸收，还能调节干扰素-γ的释放，表明其具有免疫和骨相关的调节功能。OCIL/CLEC2D 蛋白, Human (Biotinylated, HEK293, Fc-Avi) 是重组的 OCIL/CLEC2D 蛋白，由 HEK293 表达，带有 N-hFc, N-Avi 标签。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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50 μg   询价  
100 μg   询价  

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描述

The OCIL/CLEC2D protein acts as a receptor for KLRB1 and protects target cells from natural killer cell-mediated lysis. It not only inhibits osteoclast formation and bone resorption, but also regulates the release of interferon-γ, indicating that it has immune and bone-related regulatory functions. OCIL/CLEC2D Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc, N-Avi labeled tag.
研究背景

OCIL/CLEC2D 蛋白作为 KLRB1 的受体，为靶细胞提供保护，防止自然杀伤细胞介导的裂解。它不仅能抑制破骨细胞形成和骨吸收，还能调节干扰素-γ的释放，显示出其在免疫反应和骨相关过程中的调节作用。此外，OCIL/CLEC2D 表现出结合高分子量硫酸化糖胺聚糖的能力，表明其参与与细胞外成分的相互作用。在结构上，它作为具有二硫键的同二聚体存在，强调其寡聚形式在介导与免疫保护和骨稳态相关的细胞功能中的重要性。
种属

Human
表达系统

HEK293
标签

N-hFc;N-Avi
蛋白编号

Q9UHP7-1 (R60-V191)
基因 ID
蛋白结构
N-term
hFc-Avi
CLEC2D (R60-V191)
Accession # Q9UHP7-1
C-term
同用名
LLT-1; CLAX; LLT1; OCIL; CLEC2D; CLAXLLT-1; OCILmember D
分子量

68-75 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

OCIL/CLEC2D Protein, Human (Biotinylated, HEK293, Fc-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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