1. Gene
  2. CLEC2D - C-type lectin domain family 2 member D Gene

CLEC2D - C-type lectin domain family 2 member D Gene

中文名称:C 型凝集素结构域家族 2 成员 D

种属: Homo sapiens

同用名: CLAX; LLT1; OCIL

基因 ID: 29121 | 基因类型: protein coding

关于 CLEC2D

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:9,669,713-9,699,553 (from NCBI)

This gene has 16 transcripts (splice variants), 351 orthologues and 23 paralogues. Broad expression in lymph node (RPKM 24.3), appendix (RPKM 12.2) and 24 other tissues.

功能概要

该基因编码自然杀伤细胞受体 C 型凝集素家族的成员。编码的蛋白质抑制破骨细胞形成,并在 N 末端附近包含跨膜结构域以及 C 型凝集素样细胞外结构域。已经为该基因鉴定了几种选择性剪接的转录物变体。[RefSeq 提供,2010 年 10 月]

This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010]

CLEC2D 基因产物(5)

mRNA Protein Name
NM_001004419.5 NP_001004419.1 C-type lectin domain family 2 member D isoform 2
NM_001197317.3 NP_001184246.1 C-type lectin domain family 2 member D isoform 3
NM_001197318.3 NP_001184247.1 C-type lectin domain family 2 member D isoform 4
NM_001197319.3 NP_001184248.1 C-type lectin domain family 2 member D isoform 5
NM_013269.6 NP_037401.1 C-type lectin domain family 2 member D isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21572041 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
20843815 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
20843815 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CLEC2D 蛋白结构

Lectin_C

Lectin_C: Lectin C-type domain (93 - 186)

  • 0
  • 100
  • 191 a.a.
蛋白主名 其他名称

C-type lectin domain family 2 member D

C-type lectin related f

重组 CLEC2D 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77901 OCIL/CLEC2D Protein, Human (HEK293, Fc-Avi) Q9UHP7-1 (R60-V191) ≥95%
HY-P77902 OCIL/CLEC2D Protein, Human (Biotinylated, HEK293, Fc-Avi) Q9UHP7-1 (R60-V191) ≥95%

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CLEC2D RGD RGD:620070
Canis familiaris CLEC2D VGNC VGNC:39330
Macaca mulatta CLEC2D VGNC VGNC:71177
Felis catus CLEC2D VGNC VGNC:60947
Others CLEC2D NCBI