OGN/Osteoglycin 蛋白, Human (HEK293, His)

OGN/osteoglycinin cooperates with TGF-β-1 or TGF-β-2 to play a crucial role in bone formation. Its synergistic interaction with these growth factors emphasizes its importance in regulating bone homeostasis and development. OGN/Osteoglycin Protein, Human (HEK293, His) is the recombinant human-derived OGN/Osteoglycin protein, expressed by HEK293 , with C-His labeled tag. The total length of OGN/Osteoglycin Protein, Human (HEK293, His) is 278 a.a., with molecular weight of 45-60 kDa.

OGN/骨甘氨酸蛋白在骨形成中起着至关重要的作用，与 TGF-β-1 或 TGF-β-2 协同诱导这一过程。它与这些转化生长因子的功能协同作用强调了它在调节骨稳态和发育中的重要性。通过参与涉及 TGF-β 同工型的复杂信号通路，OGN 有助于分子事件的协调，最终导致骨组织的形成和维持。OGN 与 TGF-β 的协同作用凸显了其作为骨形成过程调节剂的作用，为骨骼健康和生理学的调节机制提供了潜在的见解。

Human

HEK293

C-His

P20774 (P21-F298)

4969  [NCBI]

PPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF

45-60 kDa

Greater than 95% as determined by reducing SDS-PAGE or Tris-Bis PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.