Osteomodulin 蛋白, Human (HEK293, His)

Osteomodulin is a potential contributor to the biomineralization process, exerting its functional role through α(V)β(3)-integrin binding to osteoblasts. This interaction highlights its importance in bone-related cellular activities, affecting osteoblast function and potentially bone formation and remodeling. Osteomodulin Protein, Human (HEK293, His) is the recombinant human-derived Osteomodulin protein, expressed by HEK293 , with C-His labeled tag. The total length of Osteomodulin Protein, Human (HEK293, His) is 401 a.a., with molecular weight of 50-70 KDa.

骨调节蛋白作为生物矿化过程中的潜在参与者而出现，暗示其参与了复杂的矿物质沉积机制。值得注意的是，该蛋白质在通过 α(V)β(3)-整联蛋白结合成骨细胞方面发挥着功能性作用，表明在骨相关细胞活动中具有关键的相互作用。此外，骨调节蛋白直接结合 α(V)β(3)-整合素，进一步强调了其在介导对成骨细胞功能至关重要的相互作用以及潜在影响与骨形成和重塑相关的过程中的重要性。阐明骨调节蛋白与α(V)β(3)-整合素相互作用的具体分子机制和下游效应可以为其在生物矿化和骨生理学中的作用提供有价值的见解。

Human

HEK293

C-His

Q99983 (Q21-E421)

4958  [NCBI]

QYETYQWDEDYDQEPDDDYQTGFPFRQNVDYGVPFHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTIYYGEQRSTNGQTIQLKTQVFRRFPDDDDESEDHDDPDNAHESPEQEGAEGHFDLHYYENQE

50-70 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.