2. 重组蛋白
  3. Enzymes & Regulators
  4. Hydrolases (EC 3)
  5. OTUD6A 蛋白, Human

OTUD6A 蛋白, Human

目录号: HY-P701484
产品使用指南

OTUD5 蛋白是一种具有复杂调节功能的去泛素化酶，在先天免疫系统中充当负调节因子。它对“Lys-48”和“Lys-63”连接的多聚泛素链表现出肽酶活性，并且在体外，它可以裂解“Lys-11”连接的泛素链。OTUD6A 蛋白, Human 是重组的 OTUD6A 蛋白，由 E. coli 表达，不带标签。OTUD6A 蛋白, Human 全长 288 个氨基酸。

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100 μg   询价  

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描述

The OTUD5 protein is a deubiquitinating enzyme with complex regulatory functions that acts as a negative regulator in the innate immune system. It exhibits peptidase activity against "Lys-48" and "Lys-63" linked polyubiquitin chains, and in vitro, it can cleave "Lys-11" linked ubiquitin chains. OTUD6A Protein, Human is the recombinant human-derived OTUD6A protein, expressed by E. coli , with tag free. The total length of OTUD6A Protein, Human is 288 a.a., .
研究背景

OTUD6A 是一种去泛素化酶，以其水解各种类型的多泛素链的能力而闻名。具体而言，OTUD6A 对“Lys-27”、“Lys-29”、“Lys-33”和“Lys-11”连接的多聚泛素链表现出去泛素化活性。这种酶功能涉及从底物蛋白中裂解泛素分子，有助于调节蛋白质降解和细胞信号传导途径。作为含有卵巢肿瘤结构域的去泛素酶家族的成员，OTUD6A 在调节泛素依赖性过程中发挥作用，为细胞蛋白稳态和信号传导提供微调机制。
种属

Human
表达系统

E. coli
标签

Tag Free
蛋白编号

Q7L8S5 (M1-L288)
基因 ID

139562
蛋白结构
N-term
OTUD6A (M1-L288)
Accession # Q7L8S5
C-term
同用名
OTUD6A; OTU domain-containing protein 6A; DUBA-2
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

OTUD6A Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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