PD-L2 蛋白, Human (HEK293, His-Avi)

PD-L2 Protein, operating independently of PDCD1, plays a vital role in T-cell proliferation and IFNG production. Its interaction with PDCD1 inhibits proliferation and cytokine production. The interplay between PD-L2 and PDCD1 regulates immune responses, influencing T-cell activation and function. This molecular interaction adds complexity to mechanisms governing T-cell behavior, highlighting PD-L2's versatile role in immune regulation. PD-L2 Protein, Human (HEK293, His-Avi) is the recombinant human-derived PD-L2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

PD-L2 蛋白是对 T 细胞增殖和 IFNG 产生至关重要的共刺激信号的组成部分，以不依赖 PDCD1 的方式运行。然而，它与 PDCD1 的相互作用通过阻碍细胞周期进程和细胞因子产生来抑制 T 细胞增殖。PD-L2 和 PDCD1 之间错综复杂的相互作用强调了其作为调节免疫反应、影响 T 细胞的激活和功能的调节检查点的作用。这种分子相互作用为控制 T 细胞行为的动态机制增加了一层复杂性，凸显了 PD-L2 在免疫调节中的多功能作用。

Human

HEK293

C-Avi;C-His

Q9BQ51-1 (L20-T220)

80380  [NCBI]

40-52 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.