Pentraxin 3/TSG-14 蛋白, Human (HEK293, His)

RGS5 protein is a protein that plays a key role in the regulation of G protein-coupled receptor signaling. It is involved in regulating cellular processes such as vasoconstriction and blood pressure regulation. Pentraxin 3/TSG-14 Protein, Human (HEK293, His) is the recombinant human-derived Pentraxin 3/TSG-14 protein, expressed by HEK293 , with C-10*His labeled tag and with natural variants A48D, , , , mutation. The total length of Pentraxin 3/TSG-14 Protein, Human (HEK293, His) is 364 a.a., with molecular weight of 44-50 kDa.

Pentraxin 3/TSG-14 蛋白是 pentraxin 蛋白家族的成员，由该基因编码。其表达是由炎症细胞因子响应炎症刺激而诱导的，特别是在各种间充质和上皮细胞类型中，包括内皮细胞和单核吞噬细胞。这种蛋白质在促进纤维细胞分化中发挥着至关重要的作用，并积极参与调节炎症和补体激活。此外，它还有助于血管生成和组织重塑。值得注意的是，Pentraxin 3/TSG-14 可作为多种炎症状况的生物标志物，反映了其潜在的临床意义。该基因表现出偏向表达，在骨髓 (RPKM 32.2)、阑尾 (RPKM 24.8) 和其他六个组织中表达水平升高，突出了其在多个器官的各种生理环境中的特定参与。

Immobilized Anti-TSG-14 at 1 μg/mL (100 μL/well) can bind TSG-14. The ED₅₀ for this effect is 0.04374 μg/mL.

• 
  Immobilized Anti-TSG-14 at 1 μg/mL (100 μL/well) can bind TSG-14 , The ED₅₀ for this effect is 0.04374 μg/mL.

Human

HEK293

C-10*His

NP_002843.2 (E18-S381, with natural variants A48D)

5806  [NCBI]

ENSDDYDLMYVNLDNEIDNGLHPTEDPTPCDCGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS

44-50 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization or 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.