PLA2G1B 蛋白, Mouse (HEK293, His)

The PLA2G1B protein is a secreted calcium-dependent phospholipase A2 that targets dietary phospholipids in the intestine.Phosphatidylethanolamine and phosphatidylglycerol are preferred, which hydrolyze the ester bond of the fatty acyl group at the sn-2 position.PLA2G1B Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLA2G1B protein, expressed by HEK293 , with C-6*His labeled tag.

PLA2G1B 是一种分泌型钙依赖性磷脂酶 A2，主要针对肠道中的膳食磷脂。它具有磷脂酶 A2 活性，可水解磷脂 sn-2 位脂肪酰基的酯键，优先水解磷脂酰乙醇胺和磷脂酰甘油而不是磷脂酰胆碱。PLA2G1B 可能在 N-酰基乙醇胺的生物合成中发挥至关重要的作用，调节肠道能量代谢和炎症。它以自分泌和旁分泌方式发挥作用，与 PLA2R1 受体结合后，可以调节足细胞存活和肾小球稳态。此外，PLA2G1B 具有抗蠕虫活性，在肠道上皮感染（肠道微生物群调节的过程）过程中直接影响蠕虫幼虫膜中磷脂酰乙醇胺的含量，从而影响蠕虫幼虫的完整性和传染性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Mouse

HEK293

C-6*His

Q9Z0Y2 (A16-C146)

18778  [NCBI]

AHSISPRAVWQFRNMIKCTIPGSDPLKDYNNYGCYCGLGGWGTPVDDLDRCCQTHDHCYSQAKKLESCKFLIDNPYTNTYSYSCSGSEITCSAKNNKCEDFICNCDREAAICFSKVPYNKEYKNLDTGKFC

Approximately 15.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.