PLVAP 蛋白, Human (HEK293, His)

The PLVAP protein is an endothelial cell-specific membrane protein that plays a key role in the complex structure of endothelial fenestrae by participating in the formation of septa that bridge these fenestrae. Furthermore, it plays a crucial role in the development of stomata within caveolae and transendothelial channels. PLVAP Protein, Human (HEK293, His) is the recombinant human-derived PLVAP protein, expressed by HEK293 , with N-His labeled tag. The total length of PLVAP Protein, Human (HEK293, His) is 394 a.a., with molecular weight of 50-70 kDa.

质膜囊泡相关蛋白 (PLVAP) 是一种内皮细胞独有的膜蛋白，对于形成桥接内皮窗孔的隔膜是不可或缺的。它在小窝和跨内皮通道内气孔的形成中起着至关重要的作用。PLVAP 对于调节微血管通透性至关重要，内皮窗孔促进水和溶质的受控通过，从而调节各个器官中的跨细胞流动与细胞旁流动。这种蛋白质的重要性延伸到胚胎发育，它在胚胎发育中发挥着特定的作用。在结构上，PLVAP 作为同二聚体存在，强调了其在协调复杂内皮功能中的重要性（参考：提供的信息）。

Human

HEK293

N-His

Q9BX97 (Y49-G442)

83483  [NCBI]

50-70 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, 200mM L-arginine, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.