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Pollen allergen Phl p 5 蛋白, Phleum pratense

目录号: HY-P73702
产品使用指南

花粉过敏原 Phl p 5 蛋白会引起人类过敏反应,特别是导致草花粉过敏。已知它会与对 Phleum pratense(梯牧草)过敏的个体的免疫球蛋白 E (IgE) 抗体结合,从而在这种过敏原与受影响患者中观察到的过敏反应之间建立直接联系。Pollen allergen Phl p 5 蛋白, Phleum pratense 是重组的 花粉过敏原 Phl p 5 蛋白,由 E. coli 表达,不带标签。

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描述

The Pollen allergen Phl p 5 protein induces allergic reactions in humans, particularly contributing to grass pollen allergy. It is known to bind to immunoglobulin E (IgE) antibodies in individuals who are allergic to Phleum pratense (timothy grass), establishing a direct link between this allergen and the allergic responses observed in affected patients. Pollen allergen Phl p 5 Protein, Phleum pratense is the recombinant Pollen allergen Phl p 5 protein, expressed by E. coli , with tag free. Pollen allergen Phl p 5 Protein, Phleum pratense, has molecular weight of ~28.7 kDa.

研究背景

花粉过敏原 Phl p 5 是一种源自草花粉的蛋白质,特别是 Phleum pratense(梯牧草)。它是一种强效过敏原,可引起人类过敏反应,特别是导致草花粉过敏。已知 Phl p 5 可与对 Phleum pratense 过敏的个体中存在的免疫球蛋白 E (IgE) 抗体结合。Phl p 5 和 IgE 之间的相互作用会引发过敏反应,导致易感个体出现鼻炎、结膜炎和哮喘等症状。了解 Phl p 5 的分子特征和免疫反应性对于开发治疗草花粉过敏的诊断工具和治疗策略至关重要。参考资料:所提供的信息基于截至 2022 年 1 月的一般知识,未引用具体参考资料。

种属

Others

表达系统

E. coli

标签

Tag Free

蛋白编号

Q40960 (A26-V312)

基因 ID

/

蛋白结构
N-term
Phl p 5(A26-V312)
Accession # Q40960
C-term
同用名
Pollen allergen Phl p 5; Phl p 5a; Phl p V
分子量

Approximately 28.7 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Pollen allergen Phl p 5 Protein, Phleum pratense 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Pollen allergen Phl p 5 Protein, Phleum pratense
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