1. 重组蛋白
  2. Cytokines and Growth Factors
  3. VEGF & VEGFR
  4. Prokineticin-1/EG-VEGF 蛋白, Mouse (HEK293, Fc)

Prokineticin-1/EG-VEGF 蛋白, Mouse (HEK293, Fc)

目录号: HY-P78016
产品使用指南

Prokineticin-1/EG-VEGF 蛋白诱导胃肠道平滑肌强烈收缩,刺激毛细血管内皮细胞增殖、迁移和开窗。它促进肠神经嵴细胞增殖和分化,但不促进迁移。Prokineticin-1/EG-VEGF 蛋白, Mouse (HEK293, Fc) 是重组的 Prokineticin-1/EG-VEGF 蛋白,由 HEK293 表达,带有 C-hFc 标签。

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描述

Prokineticin-1/EG-VEGF protein induces strong contraction of gastrointestinal smooth muscle and stimulates capillary endothelial cell proliferation, migration, and fenestration. It promotes enteric neural crest cell proliferation and differentiation but not migration. Prokineticin-1/EG-VEGF Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Prokineticin-1/EG-VEGF protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

Prokineticin-1/EG-VEGF 蛋白表现出胃肠道 (GI) 平滑肌的有效收缩,并刺激毛细血管内皮细胞的增殖、迁移和开窗(膜不连续性的形成)。它还促进肠神经嵴细胞的增殖和分化,但不影响其迁移。此外,Prokineticin-1/EG-VEGF 通过增强神经母细胞瘤细胞的增殖和迁移,直接促进神经母细胞瘤的进展。对PTGS2表达和前列腺素合成具有正向调节作用。此外,Prokineticin-1/EG-VEGF 可能在胎盘形成中发挥作用,并与睾丸中的正常和病理性血管生成有关。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

Q14A28-1 (A20-F105)

基因 ID
蛋白结构
N-term
EG-VEGF (A20-F105)
Accession # Q14A28-1
hFc
C-term
同用名
Prokineticin-1; EG-VEGF; Mambakine; PROK1
分子量

38-48 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Prokineticin-1/EG-VEGF Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Prokineticin-1/EG-VEGF Protein, Mouse (HEK293, Fc)
目录号:
HY-P78016
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