Prolactin 蛋白, Mouse (Sf9, His)

Prolactin proteins exhibit hormone and receptor binding activities. It regulates mammary gland development, maternal behavior, and JAK-STAT signaling. Prolactin Protein, Mouse (Sf9, His) is the recombinant mouse-derived Prolactin protein, expressed by Sf9 insect cells , with C-His labeled tag.

催乳素是一种多功能蛋白质，预计具有激素活性和催乳素受体结合活性。它在各种过程的上游发挥着关键作用，包括乳腺发育、母体行为以及通过 JAK-STAT 对受体信号通路的正向调节。催乳素存在于分泌颗粒中，在海马体、垂体、胎盘和滋养层巨细胞等关键结构中表达。该基因的人类直系同源物 PRL（催乳素）对颈动脉疾病具有影响，表明其可能参与生理和病理背景。对催乳素功能的研究可能有助于更深入地了解其不同作用及其对健康的影响。

1.Measured by its ability to promote proliferation of INS-1 cells and the ED₅₀ is typically 50-500 ng/mL.
2.Measured by its ability to induce PRL pathway activation in a Luciferase receptor Assay System. The ED50 for this effect is typically 50-500 ng/mL.

Mouse

Sf9 insect cells

C-His

NP_035294.2 (L32-C228)

19109  [NCBI]

Approximately 23-26 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, pH 7.4, 10% glycerol or pH 7.5, 10% Glycerol, 300 mM NaCl, 20 mM Tris.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.