PTH 蛋白, Human (GST)

PTH Protein, or parathyroid hormone, raises calcium levels by dissolving bone salts and inhibiting kidney excretion. It also stimulates [1-14C]-2-deoxy-D-glucose transport and glycogen synthesis in osteoblastic cells, interacting with the PTH1R receptor and binding to its N-terminal extracellular domain for these effects. PTH Protein, Human (GST) is the recombinant human-derived PTH protein, expressed by E. coli , with N-GST labeled tag.

PTH（甲状旁腺激素）通过促进骨盐溶解并抑制肾脏排泄来提高钙水平。此外，它还能刺激 [1-14C]-2-脱氧-D-葡萄糖 (2DG) 转运并促进成骨细胞中的糖原合成。PTH 通过与 PTH1R 受体相互作用，特别是与受体的 N 末端胞外结构域结合来实现这些效果。

Human

E. coli

N-GST

P01270 (S32-F65)

5741  [NCBI]

SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF

Approximately 30 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 8.0, 10% trehalose, 0.02% Tween80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.