1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3) Phosphatase
  4. Protein tyrosine phosphatases
  5. PTPRG 蛋白, Human

PTPRG 蛋白, Human

目录号: HY-P701970
COA 产品使用指南

PTPRG蛋白又称G型蛋白酪氨酸磷酸酶受体,其特征在于其酪氨酸磷酸酶活性。作为蛋白酪氨酸磷酸酶 (PTP) 家族的成员,PTPRG 参与靶蛋白中酪氨酸残基的去磷酸化。PTPRG 蛋白, Human 是重组的 PTPRG 蛋白,由 E. coli 表达,不带标签。PTPRG 蛋白, Human 全长 311 个氨基酸。

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
10 μg ¥2600 In-stock
50 μg ¥6800 In-stock
100 μg   询价  

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描述

PTPRG protein, also known as G-type protein tyrosine phosphatase receptor, is characterized by its tyrosine phosphatase activity. As a member of the protein tyrosine phosphatase (PTP) family, PTPRG is involved in the dephosphorylation of tyrosine residues in target proteins. PTPRG Protein, Human is the recombinant human-derived PTPRG protein, expressed by E. coli , with tag free. The total length of PTPRG Protein, Human is 311 a.a., .

研究背景

PTPRG蛋白,也称为G型蛋白酪氨酸磷酸酶受体,其特征在于其酪氨酸磷酸酶活性。作为蛋白酪氨酸磷酸酶 (PTP) 家族的成员,PTPRG 参与靶蛋白中酪氨酸残基的去磷酸化。这种酶活性使 PTPRG 能够调节各种细胞过程,包括细胞信号传导、生长、分化和粘附。通过其酪氨酸磷酸酶活性,PTPRG 可作为细胞内信号通路的重要调节剂,与靶蛋白上的特定酪氨酸残基相互作用并使其去磷酸化,从而影响其功能。需要进一步的研究来充分了解 PTPRG 的生理和病理作用及其作为各种以蛋白酪氨酸磷酸化失调为特征的疾病的治疗靶点的潜力。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

P23470 (P820-N1130)

基因 ID

5793

蛋白结构
N-term
PTPRG (P820-N1130)
Accession # P23470
C-term
同用名
PTPRG; Receptor-type tyrosine-protein phosphatase gamma; Protein-tyrosine phosphatase gamma; R-PTP-gamma
氨基酸序列

PIPDDMEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSN

分子量

Approximately 36 kDa.

纯度

Greater than 90% as determined by reducing SDS-PAGE.

性状

溶液.

组分

Supplied as a 0.22 μm filtered solution of 50 mM Tris-HCl, pH7.5, 200 mM NaCl, 20% glycerol, 1 mM .

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

Please use rapid thawing with running water to thaw the protein.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PTPRG Protein, Human
目录号:
HY-P701970
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