1. 重组蛋白
  2. REG-3 beta/REG3B 蛋白, Mouse

REG-3 beta/REG3B 蛋白, Mouse

目录号: HY-P702870
产品使用指南

REG-3 beta/REG3B 蛋白是一种杀菌 C 型凝集素,可对抗肠道革兰氏阳性菌和革兰氏阴性菌(鼠伤寒沙门氏菌除外)。它抑制肠炎沙门氏菌易位,防止感染。除了抗菌作用外,REG-3 beta 还具有激素功能,激活 EXTL3 受体以实现细胞特异性信号传导。在胰腺中,它显着刺激细胞增殖。REG-3 beta/REG3B 蛋白, Mouse 是重组的 REG-3 beta/REG3B 蛋白,由 E. coli 表达,不带标签。

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     可免费申领三个不同产品的试用装。

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描述

REG-3 beta/REG3B Protein, a bactericidal C-type lectin, combats intestinal Gram-positive and Gram-negative bacteria, except S.typhimurium. It inhibits S.enteritidis translocation, safeguarding against infection. Beyond antibacterial action, REG-3 beta functions hormonally, activating EXTL3 receptor for cell-specific signaling. In the pancreas, it notably stimulates cell proliferation. REG-3 beta/REG3B Protein, Mouse is the recombinant mouse-derived REG-3 beta/REG3B protein, expressed by E. coli , with no tag.

研究背景

REG-3 beta/REG3B 是一种杀菌 C 型凝集素,对多种肠道革兰氏阳性和革兰氏阴性细菌(鼠伤寒沙门氏菌除外)具有抗菌特性。它在预防肠炎沙门氏菌感染方面的潜在作用包括抑制病原体从肠腔易位到肠道和肠外组织。除了抗菌功能外,REG-3 beta 还可以作为一种激素来响应不同的刺激。当不同细胞类型分泌时,它会激活其受体 EXTL3,启动细胞特异性信号传导途径。值得注意的是,在胰腺中,REG-3 beta 具有刺激细胞增殖的能力。

种属

Mouse

表达系统

E. coli

标签

Tag Free

蛋白编号

P35230 (I38-G175)

基因 ID

18489

蛋白结构
N-term
REG3B (I38-G175)
Accession # P35230
C-term
同用名
Regenerating islet-derived protein 3-beta; REG-3-beta; Reg III-beta; PAP; PAP1
分子量

15.6 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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REG-3 beta/REG3B Protein, Mouse
目录号:
HY-P702870
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