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  4. RGM-C 蛋白, Mouse (HEK293, His)

RGM-C 蛋白, Mouse (HEK293, His)

目录号: HY-P78029
产品使用指南

RGM-C 蛋白是一种 BMP 辅助受体，对铁调素 (HAMP) 表达至关重要，通过增强 BMP 信号传导影响铁稳态。它通过与 BMP2、BMP4、BMP6、BMPR1B 和 TMPRSS6 相互作用形成分子网络，共同介导 BMP 相关信号通路并调节铁调节过程。RGM-C 蛋白, Mouse (HEK293, His) 是重组的 RGM-C 蛋白，由 HEK293 表达，带有 C-His 标签。RGM-C 蛋白, Mouse (HEK293, His) 全长 361 个氨基酸，分子量分别为 55-60 kDa & 36-40 kDa & 20-25 kDa。

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规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

RGM-C Protein, a BMP coreceptor, crucially regulates hepcidin (HAMP) expression, influencing iron homeostasis through enhanced BMP signaling. It forms a molecular network by interacting with BMP2, BMP4, BMP6, BMPR1B, and TMPRSS6, collectively mediating BMP-related signaling pathways and modulating iron regulatory processes. RGM-C Protein, Mouse (HEK293, His) is the recombinant mouse-derived RGM-C protein, expressed by HEK293, with C-His labeled tag. The total length of RGM-C Protein, Mouse (HEK293, His) is 361 a.a., with molecular weight of 55-60 kDa & 36-40 kDa & 20-25 kDa, respectively.
研究背景

RGM-C 作为骨形态发生蛋白 (BMP) 辅助受体，在铁调素 (HAMP) 表达调节中发挥关键作用，并通过增强 BMP 信号传导影响铁稳态。它与 BMP2、BMP4、BMP6、BMPR1B 和 TMPRSS6 相互作用，建立一个分子关联网络，共同发挥其在介导 BMP 相关信号传导途径和调节铁调节过程中的作用。
种属

Mouse
表达系统

HEK293
标签

C-His
蛋白编号

Q7TQ32-1 (G33-A393)
基因 ID
蛋白结构
N-term
RGM-C (G33-A393)
Accession # Q7TQ32-1
His
C-term
同用名
Hemojuvelin; Rgmc; DL-M; HFE2; HFE2AMGC23953; HJV; JH; RGMC; RGM-C
分子量

55-60 kDa&36-40 kDa&20-25 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

RGM-C Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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