S100A10 蛋白, Human (His)

S100A10 Protein is pivotal in modulating protein phosphorylation by promoting ANXA2/p36 dimerization. The ANXA2 monomer is the favored substrate for tyrosine-specific kinase activity in vitro. A heterotetramer, composed of S100A10/p11 and ANXA2/p36, highlights intricate regulatory dynamics. This interaction landscape includes SCN10A and TASOR, showcasing S100A10's multifaceted involvement in cellular processes. S100A10 Protein, Human (His) is the recombinant human-derived S100A10 protein, expressed by E. coli , with N-6*His labeled tag. The total length of S100A10 Protein, Human (His) is 96 a.a., with molecular weight of ~13 kDa.

S100A10 蛋白通过促进 ANXA2/p36 二聚化在调节蛋白磷酸化中发挥关键作用。ANXA2 单体成为体外酪氨酸特异性激酶活性的首选底物。此外，由 S100A10/p11 的两条轻链和 ANXA2/p36 的两条重链组成的异四聚体的形成强调了复杂的调控动态。这种相互作用景观扩展到包括 SCN10A 和 TASOR，强调 S100A10 在细胞过程中的多方面参与。

Human

E. coli

N-6*His

P60903 (P2-K97)

6281  [NCBI]

PSQMEHAMETMMFTFHKFAGDKGYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK

Approximately 13 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.