SARS-CoV-2 S 蛋白 (Omicron, B.1.1.529, His)

The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-CoV-2 S Protein (Omicron, B.1.1.529, His) is the recombinant Virus-derived SARS-CoV-2 S protein, expressed by HEK293 , with C-His labeled tag. SARS-CoV-2 S Protein (Omicron, B.1.1.529, His), has molecular weight of ~136.67 kDa.

SARS-Cov-2 是一种包膜阳性单链RNA病毒，可导致2019冠状病毒病(COVID-19)。
SARS-CoV-2 具有 4 种结构蛋白，包括包膜蛋白 (E)、刺突或表面糖蛋白 (S)、膜蛋白(M) 和核衣壳蛋白 (N)。
SARS-Cov-2 S glycoprotein 位于病毒颗粒的外部，使冠状病毒具有冠状外观。
ARS-Cov-2 S glycoprotein 可以介导病毒颗粒附着并进入宿主细胞，是疫苗开发、抗体治疗和基于抗原的诊断测试的重要靶标^{[1][2][3][4][5]}。

Immobilized human ACE2-Fc at 2 μg/mL (100 μL/well) can bind SARS-CoV-2 S Protein (Omicron, B.1.1.529, His) and the EC₅₀ is 4-15 ng/mL.

Virus

HEK293

C-His

P0DTC2/YP_009724390.1 (M1-P1213, with mutations A67V, HV69-70 deletion, T95I, G142D, VYY143-145 deletion, N211 deletion, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, F817P, N856K, A892P, A899P, A942P, Q954H, N969K, L981F, K986P, V987P and furin cleavage site mutants) (variant B.1.1.529)

43740568  [NCBI]

Approximately 136.67 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 25 mM sodium citrate, 200 mM NaCl, 0.02% tween 80, pH 6.0.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.