SARS-COV-2 S trimer Protein (XBB.1.16, HEK293, His)

The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein. The amino acid sequence 1261-1267a.a of the SARS-Cov-2 S glycoprotein is transmembrane. The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer, each of which consists of 1260 amino acids (residues 14-1273), divided into four structural domains: the n-terminal domain (NTD), the c-terminal domain (CTD, also known as the receptor-binding domain, RBD), and two subdomains (SD1 and SD2). SARS-COV-2 S trimer Protein (XBB.1.16, HEK293, His) is the recombinant virus-derived SARS-COV-2 S trimer, expressed by HEK293 , with C-His labeled tag. ,

SARS-Cov-2 是一种包膜阳性单链RNA病毒，可导致2019冠状病毒病(COVID-19)。
SARS-CoV-2 具有 4 种结构蛋白，包括包膜蛋白 (E)、刺突或表面糖蛋白 (S)、膜蛋白(M) 和核衣壳蛋白 (N)。
SARS-Cov-2 S glycoprotein 位于病毒颗粒的外部，使冠状病毒具有冠状外观。
ARS-Cov-2 S glycoprotein 可以介导病毒颗粒附着并进入宿主细胞，是疫苗开发、抗体治疗和基于抗原的诊断测试的重要靶标^{[1][2][3][4][5]}。

Immobilized Recombinant Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (Fc Tag) at 2 μg/mL (100 μl/well) can bind Recombinant SARS-COV-2 S trimer (XBB.1.16, HEK293, His), the EC₅₀ is ≤7 ng/mL.

Virus

HEK293

C-His

YP_009724390.1 (V16-Q1208, with mutations T19I, V83A, G142D, H146Q, E180V, Q183E, V213E, G252V, G339H, R346T, L368I, V445P, G446S, N460K, S477N, T478R, E484A, F486P, F490S, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, F817P, A892P, A899P, A942P, Q954H, N969K, K986P, V987P and furin cleavage site mutants)

43740568

136.87 kDa

Greater than 90% as determined by Tris-Bis PAGE.

溶液

Supplied as a 0.22 μm filtered solution in sodium citrate, 200 mM NaCl, 0.02% Tween-80,pH 6.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.