SCF 蛋白, Canine

SCF protein critically promotes mast cell proliferation, enhancing both myeloid and lymphoid hematopoietic progenitor proliferation in bone marrow. Additionally, SCF facilitates cell-cell adhesion and synergizes with other cytokines, potentially interleukins. As a homodimer, SCF is connected non-covalently, contributing to hematopoietic processes and immune responses. SCF Protein, Canine is the recombinant canine-derived SCF protein, expressed by E. coli , with tag free. The total length of SCF Protein, Canine is 165 a.a., with molecular weight of ~19 kDa.

SCF 蛋白在促进肥大细胞增殖中发挥着关键作用。在骨髓中培养时，它能够增强骨髓和淋巴造血祖细胞的增殖。此外，SCF 促进细胞间粘附。它与其他细胞因子（可能包括白细胞介素）协同作用。SCF 以同二聚体形式存在，通过非共价相互作用连接。

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED₅₀ for this effect is 1.679 ng/mL.

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  Measured in a cell proliferation assay using TF 1 human erythroleukemic cells. The ED₅₀ for this effect is 1.679 ng/mL, corresponding to a specific activity is 5.96×10⁵ units/mg.

Canine

E. coli

Tag Free

Q06220 (K26-A190)

403507  [NCBI]

KGICGKRVTDDVKDVTKLVANLPKDYKIALKYVPGMDVLPSHCWISVMVEQLSVSLTDLLDKFSNISEGLSNYSIIDKLVKIVDDLVECTEGYSFENVKKAPKSPELRLFTPEEFFRIFNRSIDAFKDLETVASKSSECVVSSTLSPDKDSRVSVTKPFMLPPVA

Approximately 19 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.